{"paper":{"title":"FDG kinetics in cells and tissues: a biochemically-driven compartmental approach","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.TO","authors_text":"Cecilia Marini, Giacomo Caviglia, Gianmario Sambuceti, Mara Scussolini, Vanessa Cossu","submitted_at":"2018-03-13T19:57:28Z","abstract_excerpt":"The radioactive glucose analogue 2-deoxy-2-[18F]fluoro-D-glucose (FDG) is widely used to reconstruct glucose metabolism and other biological functions in cells and tissues. The analysis of data on the time course of FDG tracer distribution is performed by the use of appropriate compartmental models. Motivated by recent results in cell biochemistry, we describe a new compartmental model aiming at the reconstruction of tracer kinetics in cells and tissues, which emphasizes the different roles of the cytosol and of the endoplasmic reticulum. Two applications of the new model are examined, that ar"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1803.05025","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}