{"paper":{"title":"Can a Quantum Support Vector Machine algorithm be utilized to identify Key Biomarkers from Multi-Omics data of COVID19 patients?","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":["cs.LG","q-bio.QM"],"primary_cat":"quant-ph","authors_text":"Chansu Yu, Jae U. Jung, Junggu Choi, Kyle L. Jung, Lara Jehi, Serpil C. Erzurum, Suan-Sin Foo, Suzy AA Comhair, Weiqiang Chen","submitted_at":"2025-04-29T16:35:38Z","abstract_excerpt":"Identifying key biomarkers for COVID-19 from high-dimensional multi-omics data is critical for advancing both diagnostic and pathogenesis research. In this study, we evaluated the applicability of the Quantum Support Vector Machine (QSVM) algorithm for biomarker-based classification of COVID-19. Proteomic and metabolomic biomarkers from two independent datasets were ranked by importance using ridge regression and grouped accordingly. The top- and bottom-ranked biomarker sets were then used to train and evaluate both classical SVM (CSVM) and QSVM models, serving as predictive and negative contr"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2505.00037","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2505.00037/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}