{"paper":{"title":"Technical Report: Time-Activity-Curve Integration in Lu-177 Therapies in Nuclear Medicine","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":[],"primary_cat":"physics.med-ph","authors_text":"Theresa Ida G\\\"otz","submitted_at":"2019-07-15T17:26:58Z","abstract_excerpt":"Currently, there is a high interest in Lu-177 targeted radionuclide therapies, which could be attributed to favourable results obtained from Lu-177 compounds targeting neuroendocrine and prostate tumours. Generally, it has been recognized that a transition from dosimetry based on planar images towards based on fully-quantitative SPECT is beneficial in terms of increased accuracy. SPECT based dosimetry could not only be used for achieving accurate absorbed dose per-organ, but even for deriving dose values for individual voxels. However, a voxel-wise determination of TACs is problematic since se"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1907.06617","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}