{"paper":{"title":"Binding of native DNA to MoS$_{2}$ nanoflakes: the role of defects and edge atoms of MoS$_{2}$ nanostructures in their biofunctionalization","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":[],"primary_cat":"physics.bio-ph","authors_text":"Alexander Glamazda, Anastasiia Svidzerska, Anna Laguta, Evgeniya Usenko, Igor Voloshin, Ludwik Adamowicz, Sergey Petrushenko, Stepan Stepanian, Victor Karachevtsev, Vladimir Valeev","submitted_at":"2025-04-29T09:05:58Z","abstract_excerpt":"In this work, the binding of native DNA to MoS$_{2}$ nanoflakes (FLs) was studied by using UV-visible absorption spectroscopy, thermal denaturation method, transmission electron microscopy (TEM), temperature-dependent dynamic light scattering (DLS), and the DFT computational-chemistry method. Analysis of the experimental data: TEM images and thermal denaturation measurements showed the binding of the biopolymer with MoS$_{2}$ FLs. An increase in the melting temperature of DNA and a decrease in the hyperchromic coefficient at binding with MoS$_{2}$ FLs indicates the formation of the DNA:MoS$_{2"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2504.20562","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2504.20562/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}