{"paper":{"title":"On the interplay between prior weight and variance of the robustification component in Robust Mixture Prior Bayesian Dynamic Borrowing approach","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":[],"primary_cat":"stat.ME","authors_text":"Gaelle Saint-Hilary, Marco Ratta, Mauro Gasparini, Pavel Mozgunov","submitted_at":"2025-09-01T12:44:57Z","abstract_excerpt":"Robust Mixture Prior (RMP) is a popular Bayesian dynamic borrowing method, which combines an informative historical distribution with a less informative component (referred as robustification component) in a mixture prior to enhance the efficiency of hybrid-control randomized trials. Current practice typically focuses solely on the selection of the prior weight that governs the relative influence of these two components, often fixing the variance of the robustification component to that of a single observation. In this study we demonstrate that the performance of RMPs critically depends on the"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2509.01435","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2509.01435/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}