{"paper":{"title":"An improved EM algorithm for solving MLE in constrained diffusion kurtosis imaging of human brain","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["stat.AP","stat.ME"],"primary_cat":"stat.CO","authors_text":"Jia Liu","submitted_at":"2015-07-24T08:43:23Z","abstract_excerpt":"The displacement distribution of a water molecular is characterized mathematically as Gaussianity without considering potential diffusion barriers and compartments. However, this is not true in real scenario: most biological tissues are comprised of cell membranes, various intracellular and extracellular spaces, and of other compartments, where the water diffusion is referred to have a non-Gaussian distribution. Diffusion kurtosis imaging (DKI), recently considered to be one sensitive biomarker, is an extension of diffusion tensor imaging, which quantifies the degree of non-Gaussianity of the "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1507.06780","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}