{"paper":{"title":"Cross-Anesthetic ECoG State Decoding Fails at the Decision Threshold, Not the Representation","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cs.AI"],"primary_cat":"q-bio.QM","authors_text":"Kunkun Zhang, Qianwei Zhou","submitted_at":"2026-07-31T17:48:32Z","abstract_excerpt":"Decoders of anesthetic state from cortical activity fail across drug classes, most notoriously ketamine, but reported accuracy cannot say whether the neural representation or only the decision threshold has failed; we separate the two in a controlled preparation with ground-truth labels. We decoded awake versus anesthetized from mouse electrocorticography (the 250-Hz-bandlimited local field potential, sampled at 1875 Hz) under leave-one-anesthetic-out evaluation across five mechanistically distinct anesthetics (isoflurane, dexmedetomidine, ketamine, propofol, and midazolam), comparing a spatia"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2608.02646","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2608.02646/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}