{"paper":{"title":"Blinking membrane patterns induced by protein binding/unbinding","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":["nlin.PS","physics.bio-ph"],"primary_cat":"cond-mat.soft","authors_text":"Hiroshi Noguchi","submitted_at":"2026-08-13T09:35:30Z","abstract_excerpt":"Nonequilibrium membrane pattern formation is studied using meshless membrane simulation. Bound proteins are considered to have two states that generate different membrane spontaneous curvatures. Protein binding and unbinding occur cyclically owing to chemical potential differences, as an off-lattice active Potts model. It is found that this cyclic binding/unbinding can induce blinking domains, with oscillating size: convex domains of the proteins with a higher spontaneous curvature grow, and subsequently, the proteins change to the other state with a lower spontaneous curvature, resulting in d"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2608.13016","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2608.13016/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}