{"paper":{"title":"Decoding Cellular Temperature via Neural Network-Aided Fluorescent Thermometry","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"physics.bio-ph","authors_text":"Bin Kang, Chao Sun, Jing-Juan Xu, Jing-Ru Wang, Tian-Tian Li, Tong Zhang, Yu-Wen Zhang, Zheng Huang","submitted_at":"2025-05-31T04:48:56Z","abstract_excerpt":"The temperature distribution within cells, especially the debates on mitochondrial temperature, has recently attracted widespread attention. Some studies have claimed that the temperature of mitochondria can reach up to 50-53 degrees Celsius. Yet others have questioned that this is due to measurement errors from fluorescent thermometry caused by other factors, like cell viscosity. Here we present a neural network-aided fluorescent thermometry and decouple the effect of cellular viscosity on temperature measurements. We found that cellular viscosity may cause significant deviations in temperatu"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2506.00389","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2506.00389/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}