{"paper":{"title":"Ancient DNA from 120-Million-Year-Old Lycoptera Fossils Reveals Evolutionary Insights","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.GN","authors_text":"Chuan-Jia Zhu, Chun-Yan Zhou, Di Wu, Fei Liang, Gang-Qiang Cao, Jin-Yu Yang, Jun-Hui Geng, Li-Juan Zhao, Li-You Qiu, Mei-Jun Li, Mei-Rong Song, Meng-Fei Tang, Ming-Jie Chen, Shu-Jie Zhang, Tian-Cang Qin, Tong-Fu Su, Wan-Qian Zhao, Wei Zhou, Xin-Ge Zhang, Yu-Qi Guo, Zeng-Yuan Tian, Zhan-Yong Guo, Zi-Xin Qi","submitted_at":"2024-12-09T14:25:43Z","abstract_excerpt":"High quality ancient DNA (aDNA) is essential for molecular paleontology. Due to DNA degradation and contamination by environmental DNA (eDNA), current research is limited to fossils less than 1 million years old. The study successfully extracted DNA from Lycoptera davidi fossils from the Early Cretaceous period, dating 120 million years ago. Using high-throughput sequencing, 1,258,901 DNA sequences were obtained. We established a rigorous protocol known as the mega screen method. Using this method, we identified 243 original in situ DNA (oriDNA) sequences, likely from the Lycoptera genome. The"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2412.06521","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2412.06521/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}