{"paper":{"title":"A simple model for conserved intracellular dynamics exhibits multiscale pattern formation, traveling protein domains and arrested coarsening of lipid domains","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["nlin.PS","physics.bio-ph"],"primary_cat":"cond-mat.soft","authors_text":"Benjamin Winkler, Markus B\\\"ar, Sergio Alonso","submitted_at":"2026-03-25T02:34:18Z","abstract_excerpt":"We model the spatiotemporal dynamics of cellular protein concentrations relevant to cell polarity near membranes composed of different lipids. Therefore, we consider a three-variable continuum model for membrane-bound protein, cytosolic protein, and the local composition of a binary lipid membrane. The model contains two globally conserved quantities: the total protein content and the average fractions of the two lipid species. It combines a conserved reaction-diffusion model for the protein dynamics, undergoing an active phase separation, with a Cahn-Hilliard equation for lipid demixing. Line"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2603.23856","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2603.23856/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}