{"paper":{"title":"Cytoskeleton-inspired, adaptive nanolipogels as superlubricating delivery vehicles","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":[],"primary_cat":"physics.bio-ph","authors_text":"Aleksei Solomonov, Avijit Mondal, Jacob Klein*, Nir Kampf, Panpan Zhao*, Roman Kamyshinsky","submitted_at":"2026-06-18T08:20:26Z","abstract_excerpt":"Phosphatidylcholine liposomes fill a special niche in alleviating osteoarthritis via intra-articular (IA) administration, attributed to their superlubricity at the articular cartilage surface, but their co-utilization as drug delivery vesicles in such therapy remains challenging as they may rupture under mechanical stress. Here, we describe cytoskeleton-inspired, supramolecular, self-assembled nanolipogels (NLGs), encompassing liposome-encased nanogels with a dynamic network formed by hydrogen bonding and cation-pi interactions, as a platform for simultaneous robust drug-delivery and massive r"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2606.19923","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2606.19923/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}