{"paper":{"title":"Label-free optical quantification of material composition of suspended virus-gold nanoparticle complexes","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"physics.bio-ph","authors_text":"Adri\\'an Gonz\\'alez, Benjamin Midtvedt, Daniel Midtvedt, Erik Ols\\'en, Fredrik Eklund, Fredrik H\\\"o\\\"ok, Giovanni Volpe, Jaroslaw Grobelny, Katarzyna Ranoszek-Soliwoda, Malgorzata Krzyzowska","submitted_at":"2023-04-15T21:18:50Z","abstract_excerpt":"The interaction between metallic and biological nanoparticles (NPs) is widely used in various biotechnology and biomedical applications. However, detailed characterization of this type of interaction is challenging due to a lack of high-throughput techniques that can quantify both size and composition of suspended NP complexes. Here, we introduce a technique called ``twilight nanoparticle tracking analysis'' (tNTA) and demonstrate that it provides a quantitative relationship between the measured optical signal and the composition of suspended dielectric-metal NP complexes. We assess the perfor"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2304.07636","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2304.07636/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}