{"paper":{"title":"Simulating Organogenesis in COMSOL: Phase-Field Based Simulations of Embryonic Lung Branching Morphogenesis","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cs.CE","math.NA"],"primary_cat":"q-bio.QM","authors_text":"Dagmar Iber, Lucas Daniel Wittwer, Roberto Croce, Sebastian Aland","submitted_at":"2016-10-28T12:47:19Z","abstract_excerpt":"Organogenesis has been studied for decades, but fundamental questions regarding the control of growth and shape remain unsolved. We have recently shown that of all proposed mathematical models only ligand-receptor based Turing models successfully reproduce the experimentally determined growth fields of the embryonic lung and thus provide a mechanism for growth control during embryonic lung development. Turing models are based on at least two coupled non-linear reaction-diffusion equations. In case of the lung model, at least two distinct layers (mesenchyme and epithelium) need to be considered"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1610.09189","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}