{"paper":{"title":"M-learner:A Flexible And Powerful Framework To Study Heterogeneous Treatment Effect In Mediation Model","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":["cs.LG","stat.ME"],"primary_cat":"stat.ML","authors_text":"Brian P. Hobbs, Hong Amy Xia, Peng Wei, Qing Liu, Tony Jiang, Xingyu Li","submitted_at":"2025-05-23T13:57:23Z","abstract_excerpt":"We propose a novel method, termed the M-learner, for estimating heterogeneous indirect and total treatment effects and identifying relevant subgroups within a mediation framework. The procedure comprises four key steps. First, we compute individual-level conditional average indirect/total treatment effect Second, we construct a distance matrix based on pairwise differences. Third, we apply tSNE to project this matrix into a low-dimensional Euclidean space, followed by K-means clustering to identify subgroup structures. Finally, we calibrate and refine the clusters using a threshold-based proce"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2505.17917","kind":"arxiv","version":3},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2505.17917/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}