{"paper":{"title":"Pulsed heterodyne Brillouin detection enables high-resolution epi-detected biomechanical microscopy and endoscopy","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"physics.optics","authors_text":"Fan Yang, Jingjing Xie, Jinrui Zhang, Junlin You, Long Zhang, Shiqing Cai, Shuai Yao, Ting Mi, Weibiao Chen, Weibing Yang, Yangxuan Liu, Yun Luo, Yun Qi, Zhisheng Yang, Zixuan Du","submitted_at":"2025-11-15T15:17:22Z","abstract_excerpt":"Brillouin microscopy enables non-contact, three-dimensional mapping of viscoelasticity in living systems, yet two long-standing limitations have constrained its biological reach: the lack of high-spectral-resolution epi-detection and the absence of practical fiber-compatible implementations. Here we introduce pulsed heterodyne Brillouin detection (PHBD), a coherent time-domain scheme addressing both challenges. By combining high-peak-power pulsed excitation with shot-noise-limited detection, PHBD reduces the optical dose by approximately two orders of magnitude relative to continuous-wave hete"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2511.12252","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2511.12252/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}