{"paper":{"title":"Single power-law rheology of crowded cytoplasm in living cells","license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","headline":"","cross_cats":[],"primary_cat":"physics.bio-ph","authors_text":"D. Mizuno, F.A.S. van Esterik, H. Ebata, H. Ise, K. Nishizawa, S. Inokuchi, Y. Tao","submitted_at":"2025-04-26T13:38:19Z","abstract_excerpt":"Cytoplasmic viscoelasticity is crucial for various intracellular processes. However, the dynamic shear modulus, $G(\\omega)$, has been reported to vary considerably, often without consistent patterns or rules, even within the same cell. Thus, uncovering the physical basis of cytoplasmic rheology, and whether any universal feature exists, remains a major challenge. Here, we employed microrheology with a 3D feedback technique to minimize artifacts such as laser phototoxicity and examined cytoplasmic viscoelasticity across varied mechanical environments, cell types, and cytoskeletal disruptions. U"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2504.18922","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2504.18922/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}