{"paper":{"title":"Modeling Time-course Gene Expression Data through Bayesian Partition Functional Principal Component Analysis","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":["stat.AP"],"primary_cat":"stat.ME","authors_text":"Daniel Temko, H\\'el\\`ene Ruffieux, Marion Kerioui, Shahin Tavakoli","submitted_at":"2026-07-13T13:40:09Z","abstract_excerpt":"High-dimensional biomarkers such as gene expression levels are now routinely measured over time, allowing biological processes to be studied dynamically rather than through cross-sectional snapshots. However, existing methods do not adequately address the central applied challenges posed by such data: simultaneously reducing dimensionality, quantifying inter-individual variability and uncovering temporal structure shared across biomarkers. We introduce Partition Functional Principal Component Analysis (PFPCA), a Bayesian model that jointly learns shared temporal patterns and clusters variables"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2607.11558","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2607.11558/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}