{"paper":{"title":"Diversity in the radiation-induced transcriptomic temporal response of mouse brain tissue regions","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":["stat.AP"],"primary_cat":"q-bio.NC","authors_text":"Joanna Polanska, Karolina Kulis, Kevin Tabury, Mohammed Abderrafi Benotmane, Sarah Baatout","submitted_at":"2024-04-29T12:46:33Z","abstract_excerpt":"A number of studies have indicated a potential association between prenatal exposure to radiation and late mental disabilities. This is believed to be due to long-term developmental changes and functional impairment of the central nervous system following radiation exposure during gestation. This study conducted a bioinformatics analysis on transcriptomic profiles from mouse brain tissue prenatally exposed to increasing doses of X-radiation. Gene expression levels were assessed in different brain regions (cortex, hippocampus, cerebellum) and collected at different time points (at 1 and 6 month"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2404.18660","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2404.18660/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}