{"paper":{"title":"Noise reduction by coupling of stochastic processes and canalization in biology","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.MN","authors_text":"Alexandre F. Ramos, John Reinitz, Jose Eduardo M. Hornos","submitted_at":"2013-02-07T23:32:19Z","abstract_excerpt":"Randomness is an unavoidable feature of the intracellular environment due to chemical reactants being present in low copy number. That phenomenon, predicted by Delbr\\\"uck long ago \\cite{delbruck40}, has been detected in both prokaryotic \\cite{elowitz02,cai06} and eukaryotic \\cite{blake03} cells after the development of the fluorescence techniques. On the other hand, developing organisms, e.g. {\\em D. melanogaster}, exhibit strikingly precise spatio-temporal patterns of protein/mRNA concentrations \\cite{gregor07b,manu09a,manu09b,boettiger09}. Those two characteristics of living organisms are in"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1302.1909","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}