{"paper":{"title":"Evidence-Grounded Frontier Mapping and Agentic Hypothesis Generation in Nanomedicine","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":[],"primary_cat":"cs.AI","authors_text":"Avi Schroeder, Ayla M. Hokke, Christiaan G.A. Viviers, Fons van der Sommen, Koen de Bruin, Mirre M. Trines, Roy van der Meel, Twan Lammers, Willem J.M. Mulder","submitted_at":"2026-05-18T09:50:11Z","abstract_excerpt":"Nanomedicine research spans delivery chemistry, immunology, imaging, biomaterials, and disease-specific translational science, yet its conceptual design space remains fragmented across a large and heterogeneous literature. To date, artificial intelligence in nanomedicine has focused primarily on property prediction and formulation optimization, with much less attention to evidence-grounded discovery support at the level of research direction selection. We introduce pArticleMap, a literature-mapping and research-hypothesis-generation system that combines article embeddings, similarity-graph ana"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2605.18144","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2605.18144/integrity.json","findings":[],"available":true,"detectors_run":[{"name":"claim_evidence","ran_at":"2026-05-19T23:41:59.103547Z","status":"completed","version":"1.0.0","findings_count":0},{"name":"ai_meta_artifact","ran_at":"2026-05-19T23:33:35.379502Z","status":"skipped","version":"1.0.0","findings_count":0}],"snapshot_sha256":"25117d842f9231f1dfa97089b9cbd27475a3332100eec7101573760282d973ba"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}