{"paper":{"title":"A Protocol to Exposure Path Analysis for Multiple Stressors Associated with Cardiovascular Disease Risk: A Novel Approach Using NHANES Data","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["q-bio.QM"],"primary_cat":"stat.AP","authors_text":"Banyun Zheng, Heqing Shen, Jiangling Liu, LongJian Liu, Ya Liu","submitted_at":"2025-03-06T12:11:29Z","abstract_excerpt":"Background: Multiple medical and non-medical stressors, along with the complicity of their exposure pathways, have posted significant challenges to the epidemiological interpretation of the non-communicable diseases, including cardiovascular disease (CVD). Objective: To develop a protocol for deconstructing the complex exposure pathways linking various stressors to adverse outcomes and to elucidate the sequential determinants contributing to CVD risk in depth. Methods: In this study, we developed a Path-Lasso approach, rooted in Adaptive Lasso regression, to construct the network and paths to "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2503.04365","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2503.04365/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}