{"paper":{"title":"Long-term sustained malaria control leads to inbreeding and fragmentation of Plasmodium vivax populations","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.PE","authors_text":"Alyssa E. Barry, Andreea Waltmann, Andrew W. Darcy, Celine Barnadas, Charlie Jennison, Cristian Koepfli, G.L. Abby Harrison, Harin Karunajeewa, Ivo Mueller, James Kazura, Lyndes Wini, Maxine Whittaker, Melanie Bahlo, Natacha Tessier, Sarah Boyd, Stephan Karl","submitted_at":"2016-12-19T05:07:32Z","abstract_excerpt":"Plasmodium vivax populations are more resistant to malaria control strategies than Plasmodium falciparum, maintaining high genetic diversity and gene flow even at low transmission. To quantify the impact of declining transmission on P. vivax populations, we investigated population genetic structure over time during intensified control efforts and over a wide range of transmission intensities and spatial scales in the Southwest Pacific. Analysis of 887 P. vivax microsatellite haplotypes (Papua New Guinea, PNG = 443, Solomon Islands = 420, Vanuatu =24) revealed substantial population structure a"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1612.06050","kind":"arxiv","version":3},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}