{"paper":{"title":"Successes and failures of simple statistical physics models for a network of real neurons","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["q-bio.NC"],"primary_cat":"physics.bio-ph","authors_text":"Carlos D. Brody, David W. Tank, Jeffrey L. Gauthier, Leenoy Meshulam, William Bialek","submitted_at":"2021-12-29T18:42:26Z","abstract_excerpt":"Biological networks exhibit complex, coordinated patterns of activity. Can these patterns be captured precisely in simple models? Here we use measurements of simultaneous activity in 1000+ neurons in the mouse brain to test the validity of models grounded in statistical physics. When cells are dense samples from a small region, we find extremely detailed quantitative agreement between theory and experiment; sparse samples from larger regions lead to model failures. These results show we can aspire to more than qualitative agreement between simplifying theoretical ideas and the detailed behavio"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2112.14735","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2112.14735/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}