{"paper":{"title":"Toward Joint Prediction of a Longitudinal Marker and a Terminal Event: A bivariate discrete-time framework","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"stat.ME","authors_text":"Daniel Kramer, Harrison Reeder, Rajarshi Mukherjee, Rui Duan, Sebastien Haneuse, Stephanie Armbruster","submitted_at":"2026-07-10T19:28:01Z","abstract_excerpt":"Sudden cardiac death (SCD) is a leading cause of death in the U.S. Patients at elevated risk of SCD are primarily treated with an implantable cardioverter-defibrillator (ICD), which can prevent cardiovascular death but often causes severe side effects, such as reduced quality of life from shock-induced pain. Decisions about ICD treatment involve complex personal trade-offs across multiple health events, including mortality and quality of life. While prediction tools could help patients and providers weigh these trade-offs, they focus on univariate outcomes, treating other clinical endpoints as"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2607.09931","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2607.09931/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}