{"paper":{"title":"Coupling Anisotropic Curvature and Nematic Order: Mechanisms of Membrane Shape Remodeling","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":["physics.bio-ph"],"primary_cat":"cond-mat.soft","authors_text":"Ale\\v{s} Igli\\v{c}, Luka Mesarec, Mitja Drab, Nir S. Gov, Samo Peni\\v{c}, Veronika Kralj-Igli\\v{c}, Yoav Ravid","submitted_at":"2025-06-17T09:40:23Z","abstract_excerpt":"This study theoretically investigates how anisotropic curved membrane components (CMCs) control vesicle morphology through curvature sensing, nematic alignment, topological defects, and volume constraints. By comparing arc-shaped and saddle-shaped CMCs, we identify a rich spectrum of steady-state phases. For fully CMC-covered vesicles, arc-shaped components drive a pearling-to-cylinder transition as nematic interactions strengthen, while on partially CMC-covered vesicles, the saddle-shaped CMCs stabilize necks between the convex regions of bare membrane. We map the steady-state shapes of vesic"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2506.14347","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2506.14347/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}