{"paper":{"title":"The Coupled TuFF-BFF Algorithm for Automatic 3D Segmentation of Microglia","license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","headline":"","cross_cats":[],"primary_cat":"eess.IV","authors_text":"Jeremy Thompson, Scott T. Acton, Tajie Harris, Tiffany Ly","submitted_at":"2018-02-12T16:07:01Z","abstract_excerpt":"We propose an automatic 3D segmentation algorithm for multiphoton microscopy images of microglia. Our method is capable of segmenting tubular and blob-like structures from noisy images. Current segmentation techniques and software fail to capture the fine processes and soma of the microglia cells, useful for the study of the microglia role in the brain during healthy and diseased states. Our coupled tubularity flow field (TuFF)-blob flow field (BFF) method evolves a level set toward the object boundary using the directional tubularity and blobness measure of 3D images. Our method found a 20% p"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1802.04156","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}