{"paper":{"title":"Fast and label-free 3D virtual H&E histology via active modulation-assisted dynamic full-field OCT","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["physics.bio-ph","physics.optics"],"primary_cat":"physics.med-ph","authors_text":"Bin He, Chengming Wang, Guihuai Wang, Panqi Yang, Ping Xue, Ruizhi Xue, Shu Wang, Shuwei Zhang, Yejiong Shi, Yuzhe Ying, Zhangwei Hu, Zhengyu Chen, Zichen Yin","submitted_at":"2024-04-27T03:22:10Z","abstract_excerpt":"Pathological features are the gold standard for tumor diagnosis, guiding treatment and prognosis. However, standard histopathological process is labor-intensive and time-consuming, while frozen sections have lower accuracy. Dynamic full-field optical coherence tomography (D-FFOCT) offers rapid histologic information by measuring the subcellular dynamics of fresh, unprocessed tissues. However, D-FFOCT images suffer from abrupt shifts in hue and brightness, which is confusing for pathologists and diminish their interpretability and reliability. Here, we present active phase modulation-assisted D"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2404.19641","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2404.19641/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}