{"paper":{"title":"Designing Covalent Organic Framework-based Light-driven Microswimmers towards Intraocular Theranostic Applications","license":"http://creativecommons.org/licenses/by-nc-nd/4.0/","headline":"","cross_cats":["cond-mat.mtrl-sci","cond-mat.soft","q-bio.QM"],"primary_cat":"physics.bio-ph","authors_text":"Amirreza Aghakhani, Andr\\'es Rodr\\'iguez-Camargo, Bettina V. Lotsch, Erdost Yildiz, Filip Podjaski, Liang Yao, Metin Sitti, Mukrime Birgul Akolpoglu, Paul Wrede, Varun Sridhar, Xianglong Lyu","submitted_at":"2023-01-10T15:39:48Z","abstract_excerpt":"Even micromachines with tailored functionalities enable targeted therapeutic applications in biological environments, their controlled motion in biological media and drug delivery functions usually require sophisticated designs and complex propulsion apparatuses for practical applications. Covalent organic frameworks (COFs), new chemically versatile and nanoporous materials, offer microscale multi-purpose solutions, which are not explored in light-driven micromachines. We describe and compare two different types of COFs, uniformly spherical TABP-PDA-COF sub-micron particles and texturally high"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2301.13787","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2301.13787/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}