{"paper":{"title":"Genome Sequencing Highlights Genes Under Selection and the Dynamic Early History of Dogs","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.GN","authors_text":"Adam H. Freedman, Adam R. Boyko, Adam Siepel, Belen Lorente-Galdos, Can Alkan, Carles Vil\\`a, Carlos D. Bustamante, Clarence Lee, Diego Ortega-Del Vecchyo, Elaine A. Ostrander, Eli Geffen, Eunjung Han, Farhad Hormozdiari, Heidi G. Parker, Holly Beale, Ilan Gronau, John Novembre, Josip Kusak, Kevin Squire, Marco Galaverni, Oscar Ramirez, Pedro M. Silva, Peter Marx, Rena M. Schweizer, Robert K. Wayne, Stanley F. Nelson, Timothy T. Harkins, Tomas Marques-Bonet, Vasisht Tadigotla, Zhenxin Fan","submitted_at":"2013-05-31T13:17:04Z","abstract_excerpt":"To identify genetic changes underlying dog domestication and reconstruct their early evolutionary history, we analyzed novel high-quality genome sequences of three gray wolves, one from each of three putative centers of dog domestication, two ancient dog lineages (Basenji and Dingo) and a golden jackal as an outgroup. We find dogs and wolves diverged through a dynamic process involving population bottlenecks in both lineages and post-divergence gene flow, which confounds previous inferences of dog origins. In dogs, the domestication bottleneck was severe involving a 17 to 49-fold reduction in "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1305.7390","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}