{"paper":{"title":"Concurrent and Accurate RNA Sequencing on Multicore Platforms","license":"http://creativecommons.org/licenses/by-nc-sa/3.0/","headline":"","cross_cats":["cs.DC","q-bio.QM"],"primary_cat":"q-bio.GN","authors_text":"(2) Computational Genomics Institute, Castell\\'on, Centro de Investigaci\\'on Pr\\'incipe Felipe, Enrique S. Quintana-Ort\\'i (1) ((1) Dpto. de Ingenier\\'ia y Ciencia de los Computadores, H\\'ector Mart\\'inez (1), Ignacio Medina (2), Joaqu\\'in Dopazo (2), Joaqu\\'in T\\'arraga (2), Maribel Castillo (1), Sergio Barrachina (1), Spain, Spain), Universidad Jaume I, Valencia","submitted_at":"2013-04-02T16:34:36Z","abstract_excerpt":"In this paper we introduce a novel parallel pipeline for fast and accurate mapping of RNA sequences on servers equipped with multicore processors. Our software, named HPG-Aligner, leverages the speed of the Burrows-Wheeler Transform to map a large number of RNA fragments (reads) rapidly, as well as the accuracy of the Smith-Waterman algorithm, that is employed to deal with conflictive reads. The aligner is complemented with a careful strategy to detect splice junctions based on the division of RNA reads into short segments (or seeds), which are then mapped onto a number of candidate alignment "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1304.0681","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}