{"paper":{"title":"Towards Virtual Clinical Trials of Radiology AI with Conditional Generative Modeling","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cs.AI","cs.LG"],"primary_cat":"cs.CV","authors_text":"Aditya V. Kulkarni, Benjamin D. Killeen, Bohua Wan, Mathias Unberath, Michael Oberst, Nathan Drenkow, Paul H. Yi","submitted_at":"2025-02-13T15:53:52Z","abstract_excerpt":"Artificial intelligence (AI) is poised to transform healthcare by enabling personalized and efficient care through data-driven insights. Although radiology is at the forefront of AI adoption, in practice, the potential of AI models is often overshadowed by severe failures to generalize: AI models can have performance degradation of up to 20% when transitioning from controlled test environments to clinical use by radiologists. This mismatch raises concerns that radiologists will be misled by incorrect AI predictions in practice and/or grow to distrust AI, rendering these promising technologies "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2502.09688","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2502.09688/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}