{"paper":{"title":"AMPA, NMDA and GABAA receptor mediated network burst dynamics in cortical cultures in vitro","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["q-bio.CB"],"primary_cat":"q-bio.NC","authors_text":"2), (2) Bernstein Center Freiburg & Department of Microsystems Engineering, Albert-Ludwig University of Freiburg, Finland, Freiburg, Germany), H. Teppola (1, IMTEK, M.-L. Linne (1), S. Okujeni (2), Tampere, Tampere University of Technology, U. Egert (2) ((1) Department of Signal Processing","submitted_at":"2018-02-01T09:50:29Z","abstract_excerpt":"In this work we study the excitatory AMPA, and NMDA, and inhibitory GABAA receptor mediated dynamical changes in neuronal networks of neonatal rat cortex in vitro. Extracellular network-wide activity was recorded with 59 planar electrodes simultaneously under different pharmacological conditions. We analyzed the changes of overall network activity and network-wide burst frequency between baseline and AMPA receptor (AMPA-R) or NMDA receptor (NMDA-R) driven activity, as well as between the latter states and disinhibited activity. Additionally, spatiotemporal structures of pharmacologically modif"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1802.00217","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}