{"paper":{"title":"Efficient Doubly Adaptive Biased Coin Designs for Multiple Treatments","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["math.PR","stat.ME","stat.TH"],"primary_cat":"math.ST","authors_text":"Zhang Li-Xin","submitted_at":"2026-07-19T10:21:35Z","abstract_excerpt":"The randomness, efficiency (power and variability), and desirable allocation proportions are important components for evaluating a response-adaptive design in clinical trials and conflicted demands in applications. The aim of this paper is to provide designs dealing with these dilemmas.\n  We first give a general framework for\n  efficient response-adaptive randomization procedures that attain the Cram\\'er-Rao lower bounds of the allocation variances for any desired allocation proportions. The general framework is flexible for us to define new families of efficient designs with good properties f"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2607.17176","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2607.17176/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}