{"paper":{"title":"Computed Tomography (CT)-derived Cardiovascular Flow Estimation Using Physics-Informed Neural Networks Improves with Sinogram-based Training: A Simulation Study","license":"http://creativecommons.org/licenses/by-nc-sa/4.0/","headline":"","cross_cats":["cs.CV","cs.LG","physics.med-ph"],"primary_cat":"eess.IV","authors_text":"Alejandro Gonzalo Grande, Francisco Contijoch, Gurnoor Singh Khurana, Jinyuxuan Guo, Juan C. del Alamo","submitted_at":"2025-11-05T21:44:47Z","abstract_excerpt":"Background: Non-invasive imaging-based assessment of blood flow plays a critical role in evaluating heart function and structure. Computed Tomography (CT) is a widely-used imaging modality that can robustly evaluate cardiovascular anatomy and function, but direct methods to estimate blood flow velocity from movies of contrast evolution have not been developed.\n  Purpose: This study evaluates the impact of CT imaging on Physics-Informed Neural Networks (PINN)-based flow estimation and proposes an improved framework, SinoFlow, which uses sinogram data directly to estimate blood flow.\n  Methods: "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2511.03876","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2511.03876/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"}