TMLE-PR and A-TMLE borrow information from non-subgroup participants in RCTs to improve efficiency of subgroup-specific treatment effect estimation, demonstrated on Black and Asian subgroups in the LEADER trial.
Highly adaptive empirical risk minimization with principal components.arXiv preprint arXiv:2603.18204,
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Improving the Efficiency of Subgroup Analysis in Randomized Controlled Trials with TMLE
TMLE-PR and A-TMLE borrow information from non-subgroup participants in RCTs to improve efficiency of subgroup-specific treatment effect estimation, demonstrated on Black and Asian subgroups in the LEADER trial.