IDC combines idealisation, discretisation and a minimum-distance estimator on coupled Markov models to infer cooperativity from ensemble voltage-clamp currents, with an asymptotic consistency guarantee, and finds gramicidin D channels act independently.
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Robust inference of cooperative behaviour of multiple ion channels in voltage-clamp recordings
IDC combines idealisation, discretisation and a minimum-distance estimator on coupled Markov models to infer cooperativity from ensemble voltage-clamp currents, with an asymptotic consistency guarantee, and finds gramicidin D channels act independently.