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arxiv: 1012.0893 · v2 · pith:PCAWPC2Mnew · submitted 2010-12-04 · ❄️ cond-mat.soft · cond-mat.stat-mech· physics.bio-ph

DNA translocation through nanopores with salt gradients: The role of osmotic flow

classification ❄️ cond-mat.soft cond-mat.stat-mechphysics.bio-ph
keywords captureflownanoporesosmoticratesalttranslocationacross
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Recent experiments of translocation of double stranded DNA through nanopores [M. Wanunu \textit{et al.} Nature Nanotech. {\bf 5}, 160 (2010)] reveal that the DNA capture rate can be significantly influenced by a salt gradient across the pore. We show that osmotic flow combined with electrophoretic effects can quantitatively explain the experimental data on the salt-gradient dependence of the capture rate.

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