{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2009:2664GJ6ONBMP4SGSKJEAR4KNVW","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"16c834fa548faa3120dfd3de6f1b74c2288ff34f78cb0638da1b4e4a4df955ba","cross_cats_sorted":["q-bio.BM"],"license":"http://creativecommons.org/licenses/by/3.0/","primary_cat":"q-bio.MN","submitted_at":"2009-12-22T17:36:07Z","title_canon_sha256":"40e5e2ef93107ad5c7e18cb2ace21acdca4f9730eb8c7b3d9469f36e8ed2991f"},"schema_version":"1.0","source":{"id":"0912.4465","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"0912.4465","created_at":"2026-05-18T04:41:05Z"},{"alias_kind":"arxiv_version","alias_value":"0912.4465v2","created_at":"2026-05-18T04:41:05Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.0912.4465","created_at":"2026-05-18T04:41:05Z"},{"alias_kind":"pith_short_12","alias_value":"2664GJ6ONBMP","created_at":"2026-05-18T12:25:58Z"},{"alias_kind":"pith_short_16","alias_value":"2664GJ6ONBMP4SGS","created_at":"2026-05-18T12:25:58Z"},{"alias_kind":"pith_short_8","alias_value":"2664GJ6O","created_at":"2026-05-18T12:25:58Z"}],"graph_snapshots":[{"event_id":"sha256:d399ecf64d6582a7e189279c45a3a7477ca17c554e3291ebf19751b3417e7f87","target":"graph","created_at":"2026-05-18T04:41:05Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Post-translational modifications of histone proteins are an important factor in epigenetic control that serve to regulate transcription, depending on the particular modification states of the histone proteins. We study the stochastic dynamics of histone protein states, taking into account a feedback mechanism where modified nucleosomes recruit enzymes that diffuse to adjacent nucleosomes. We map the system onto a quantum spin system whose dynamics is generated by a non-Hermitian Hamiltonian. Making an ansatz for the solution as a tensor product state leads to nonlinear partial differential equ","authors_text":"C. Gils, J.L. Wrana, W.K. Abou Salem","cross_cats":["q-bio.BM"],"headline":"","license":"http://creativecommons.org/licenses/by/3.0/","primary_cat":"q-bio.MN","submitted_at":"2009-12-22T17:36:07Z","title":"A quantum spin approach to histone dynamics"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"0912.4465","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:e8d263aa18650ac936feec5e1786479068b510b17807b3b413c938d31277ff6e","target":"record","created_at":"2026-05-18T04:41:05Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"16c834fa548faa3120dfd3de6f1b74c2288ff34f78cb0638da1b4e4a4df955ba","cross_cats_sorted":["q-bio.BM"],"license":"http://creativecommons.org/licenses/by/3.0/","primary_cat":"q-bio.MN","submitted_at":"2009-12-22T17:36:07Z","title_canon_sha256":"40e5e2ef93107ad5c7e18cb2ace21acdca4f9730eb8c7b3d9469f36e8ed2991f"},"schema_version":"1.0","source":{"id":"0912.4465","kind":"arxiv","version":2}},"canonical_sha256":"d7bdc327ce6858fe48d2524808f14dada2a538f6c065e7ae5468c520a08005db","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"d7bdc327ce6858fe48d2524808f14dada2a538f6c065e7ae5468c520a08005db","first_computed_at":"2026-05-18T04:41:05.164963Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T04:41:05.164963Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"gNqTxQpWRuF5RltJdUuPlRhZTZQ/ny5oPynkioxScWrkLvuppeT5VAGrQ/ivAub8OhncBwUpsN7mvVckx78JCg==","signature_status":"signed_v1","signed_at":"2026-05-18T04:41:05.165339Z","signed_message":"canonical_sha256_bytes"},"source_id":"0912.4465","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:e8d263aa18650ac936feec5e1786479068b510b17807b3b413c938d31277ff6e","sha256:d399ecf64d6582a7e189279c45a3a7477ca17c554e3291ebf19751b3417e7f87"],"state_sha256":"d568e40586718064f678c59518b7fb6faa4c7fb227f8e54d93c53822eb1e853a"}