{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2016:2JOMTEI33IOHFXDV3V5Z5HCFI7","short_pith_number":"pith:2JOMTEI3","canonical_record":{"source":{"id":"1605.01573","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.ML","submitted_at":"2016-05-05T12:50:44Z","cross_cats_sorted":[],"title_canon_sha256":"b2ea881e70523da4bfade60fad956b718302f73040959efdf3b3563d10fac0ef","abstract_canon_sha256":"b7cedbfb6bcbcfa7ee96e8f50f2a817ff73e3443ab95ab595319b0d6006606f2"},"schema_version":"1.0"},"canonical_sha256":"d25cc9911bda1c72dc75dd7b9e9c4547ce742b55c6a1ae9a146430fdf517fffa","source":{"kind":"arxiv","id":"1605.01573","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1605.01573","created_at":"2026-05-18T01:15:33Z"},{"alias_kind":"arxiv_version","alias_value":"1605.01573v1","created_at":"2026-05-18T01:15:33Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1605.01573","created_at":"2026-05-18T01:15:33Z"},{"alias_kind":"pith_short_12","alias_value":"2JOMTEI33IOH","created_at":"2026-05-18T12:29:55Z"},{"alias_kind":"pith_short_16","alias_value":"2JOMTEI33IOHFXDV","created_at":"2026-05-18T12:29:55Z"},{"alias_kind":"pith_short_8","alias_value":"2JOMTEI3","created_at":"2026-05-18T12:29:55Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2016:2JOMTEI33IOHFXDV3V5Z5HCFI7","target":"record","payload":{"canonical_record":{"source":{"id":"1605.01573","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.ML","submitted_at":"2016-05-05T12:50:44Z","cross_cats_sorted":[],"title_canon_sha256":"b2ea881e70523da4bfade60fad956b718302f73040959efdf3b3563d10fac0ef","abstract_canon_sha256":"b7cedbfb6bcbcfa7ee96e8f50f2a817ff73e3443ab95ab595319b0d6006606f2"},"schema_version":"1.0"},"canonical_sha256":"d25cc9911bda1c72dc75dd7b9e9c4547ce742b55c6a1ae9a146430fdf517fffa","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:15:33.279210Z","signature_b64":"daaq+qr9ECRJybI1YEc69jsWr90zTmTss0dNX2QOVD8LOleg2iWxp8PJ5HP74dN7JD6yUMV8Lwwqqq1eorghAA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"d25cc9911bda1c72dc75dd7b9e9c4547ce742b55c6a1ae9a146430fdf517fffa","last_reissued_at":"2026-05-18T01:15:33.278462Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:15:33.278462Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1605.01573","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:15:33Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"Fs86FiF3Qq6+ULy+6Q7O+yY2ElEkXLsTv5YBm47LIjVIqYzj6tlzlsYvMpxzsIUBHe7JsuxGFP8V2jkYOakDCw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-27T12:19:30.869010Z"},"content_sha256":"cac5045a9b675906a76eedd31a64a9617389641448d4f93e6d6034eac6681a79","schema_version":"1.0","event_id":"sha256:cac5045a9b675906a76eedd31a64a9617389641448d4f93e6d6034eac6681a79"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2016:2JOMTEI33IOHFXDV3V5Z5HCFI7","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Observational-Interventional Priors for Dose-Response Learning","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"stat.ML","authors_text":"Ricardo Silva","submitted_at":"2016-05-05T12:50:44Z","abstract_excerpt":"Controlled interventions provide the most direct source of information for learning causal effects. In particular, a dose-response curve can be learned by varying the treatment level and observing the corresponding outcomes. However, interventions can be expensive and time-consuming. Observational data, where the treatment is not controlled by a known mechanism, is sometimes available. Under some strong assumptions, observational data allows for the estimation of dose-response curves. Estimating such curves nonparametrically is hard: sample sizes for controlled interventions may be small, whil"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1605.01573","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:15:33Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"MP6bKRpxssKq/Mz+w5n5TvKtTVQl8Daa6DshJL6B3J2q2lJBIYGEhpzkBzQzTna1tqn5uzaimtq0oUY0ZgBzDw==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-27T12:19:30.869578Z"},"content_sha256":"f6f697862f719a2bf1acd3d3f42c587693700397f088b13d975633fcc01048fd","schema_version":"1.0","event_id":"sha256:f6f697862f719a2bf1acd3d3f42c587693700397f088b13d975633fcc01048fd"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/2JOMTEI33IOHFXDV3V5Z5HCFI7/bundle.json","state_url":"https://pith.science/pith/2JOMTEI33IOHFXDV3V5Z5HCFI7/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/2JOMTEI33IOHFXDV3V5Z5HCFI7/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-27T12:19:30Z","links":{"resolver":"https://pith.science/pith/2JOMTEI33IOHFXDV3V5Z5HCFI7","bundle":"https://pith.science/pith/2JOMTEI33IOHFXDV3V5Z5HCFI7/bundle.json","state":"https://pith.science/pith/2JOMTEI33IOHFXDV3V5Z5HCFI7/state.json","well_known_bundle":"https://pith.science/.well-known/pith/2JOMTEI33IOHFXDV3V5Z5HCFI7/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2016:2JOMTEI33IOHFXDV3V5Z5HCFI7","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"b7cedbfb6bcbcfa7ee96e8f50f2a817ff73e3443ab95ab595319b0d6006606f2","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.ML","submitted_at":"2016-05-05T12:50:44Z","title_canon_sha256":"b2ea881e70523da4bfade60fad956b718302f73040959efdf3b3563d10fac0ef"},"schema_version":"1.0","source":{"id":"1605.01573","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1605.01573","created_at":"2026-05-18T01:15:33Z"},{"alias_kind":"arxiv_version","alias_value":"1605.01573v1","created_at":"2026-05-18T01:15:33Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1605.01573","created_at":"2026-05-18T01:15:33Z"},{"alias_kind":"pith_short_12","alias_value":"2JOMTEI33IOH","created_at":"2026-05-18T12:29:55Z"},{"alias_kind":"pith_short_16","alias_value":"2JOMTEI33IOHFXDV","created_at":"2026-05-18T12:29:55Z"},{"alias_kind":"pith_short_8","alias_value":"2JOMTEI3","created_at":"2026-05-18T12:29:55Z"}],"graph_snapshots":[{"event_id":"sha256:f6f697862f719a2bf1acd3d3f42c587693700397f088b13d975633fcc01048fd","target":"graph","created_at":"2026-05-18T01:15:33Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Controlled interventions provide the most direct source of information for learning causal effects. In particular, a dose-response curve can be learned by varying the treatment level and observing the corresponding outcomes. However, interventions can be expensive and time-consuming. Observational data, where the treatment is not controlled by a known mechanism, is sometimes available. Under some strong assumptions, observational data allows for the estimation of dose-response curves. Estimating such curves nonparametrically is hard: sample sizes for controlled interventions may be small, whil","authors_text":"Ricardo Silva","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.ML","submitted_at":"2016-05-05T12:50:44Z","title":"Observational-Interventional Priors for Dose-Response Learning"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1605.01573","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:cac5045a9b675906a76eedd31a64a9617389641448d4f93e6d6034eac6681a79","target":"record","created_at":"2026-05-18T01:15:33Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"b7cedbfb6bcbcfa7ee96e8f50f2a817ff73e3443ab95ab595319b0d6006606f2","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"stat.ML","submitted_at":"2016-05-05T12:50:44Z","title_canon_sha256":"b2ea881e70523da4bfade60fad956b718302f73040959efdf3b3563d10fac0ef"},"schema_version":"1.0","source":{"id":"1605.01573","kind":"arxiv","version":1}},"canonical_sha256":"d25cc9911bda1c72dc75dd7b9e9c4547ce742b55c6a1ae9a146430fdf517fffa","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"d25cc9911bda1c72dc75dd7b9e9c4547ce742b55c6a1ae9a146430fdf517fffa","first_computed_at":"2026-05-18T01:15:33.278462Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T01:15:33.278462Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"daaq+qr9ECRJybI1YEc69jsWr90zTmTss0dNX2QOVD8LOleg2iWxp8PJ5HP74dN7JD6yUMV8Lwwqqq1eorghAA==","signature_status":"signed_v1","signed_at":"2026-05-18T01:15:33.279210Z","signed_message":"canonical_sha256_bytes"},"source_id":"1605.01573","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:cac5045a9b675906a76eedd31a64a9617389641448d4f93e6d6034eac6681a79","sha256:f6f697862f719a2bf1acd3d3f42c587693700397f088b13d975633fcc01048fd"],"state_sha256":"b9648b2754ce19eeea1f175c284f498e64f2314135853494ce53d11a4c88847c"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"25I6hcxAEyvIwQiJMEFk9C49HWzdHR7Sng5VUVmQXeBp4aavmVmYHjAP1/NvCqC72iJCu85i2jDsVqcVgvuUCg==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-27T12:19:30.873023Z","bundle_sha256":"602b52034b53c57e3e2d6cac4f92f265de5cf75d4f3fcdde39a19eb052ea597a"}}