{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2015:2ME72D5U6CQNYVFKUYFS233LV4","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"628dd5f927043a51f65c4cb1ba9dcd48f4b8c034c220dc12e6122871504a1cc5","cross_cats_sorted":["math.NA"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.TO","submitted_at":"2015-12-12T17:33:55Z","title_canon_sha256":"3b53634a220958da851c153cbe7f50854214b64aae14201bdc669e20f915c9f7"},"schema_version":"1.0","source":{"id":"1601.05436","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1601.05436","created_at":"2026-05-18T01:11:45Z"},{"alias_kind":"arxiv_version","alias_value":"1601.05436v1","created_at":"2026-05-18T01:11:45Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1601.05436","created_at":"2026-05-18T01:11:45Z"},{"alias_kind":"pith_short_12","alias_value":"2ME72D5U6CQN","created_at":"2026-05-18T12:29:02Z"},{"alias_kind":"pith_short_16","alias_value":"2ME72D5U6CQNYVFK","created_at":"2026-05-18T12:29:02Z"},{"alias_kind":"pith_short_8","alias_value":"2ME72D5U","created_at":"2026-05-18T12:29:02Z"}],"graph_snapshots":[{"event_id":"sha256:0a6ac333e98a500419d4263f5e1bb1534c1d319dc23566434806752168239895","target":"graph","created_at":"2026-05-18T01:11:45Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Prostate cancer is one of the most common cancers in men. It is characterized by a slow growth and it can be diagnosed in an early stage by observing the Prostate Specific Antigen (PSA). However, a relapse after the primary therapy could arise and different growth characteristics of the new tumor are observed. In order to get a better understanding of the phenomenon, a mathematical model involving several parameters is considered. To estimate the values of the parameters identifying the disease risk level a novel approach, based on combining Particle Swarm Optimization (PSO) with a meshfree in","authors_text":"Emma Perracchione, Ilaria Stura","cross_cats":["math.NA"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.TO","submitted_at":"2015-12-12T17:33:55Z","title":"An RBF-PSO Based Approach for Modeling Prostate Cancer"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1601.05436","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:ddb8868acbb2a451fc87f0ff4a679a2990448a50d7be79a2c738d4c83c95c404","target":"record","created_at":"2026-05-18T01:11:45Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"628dd5f927043a51f65c4cb1ba9dcd48f4b8c034c220dc12e6122871504a1cc5","cross_cats_sorted":["math.NA"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.TO","submitted_at":"2015-12-12T17:33:55Z","title_canon_sha256":"3b53634a220958da851c153cbe7f50854214b64aae14201bdc669e20f915c9f7"},"schema_version":"1.0","source":{"id":"1601.05436","kind":"arxiv","version":1}},"canonical_sha256":"d309fd0fb4f0a0dc54aaa60b2d6f6baf36e9a335903528a51c38de6542cd35ed","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"d309fd0fb4f0a0dc54aaa60b2d6f6baf36e9a335903528a51c38de6542cd35ed","first_computed_at":"2026-05-18T01:11:45.099147Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T01:11:45.099147Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"vc5bXS7iRNV0zTOwaRnBtXhXm3bTA2MmU/BDm/XpfECiePO09rypuNaCJNXRb3xM0SeA5e01nVLCJgjkd+W8Bg==","signature_status":"signed_v1","signed_at":"2026-05-18T01:11:45.099476Z","signed_message":"canonical_sha256_bytes"},"source_id":"1601.05436","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:ddb8868acbb2a451fc87f0ff4a679a2990448a50d7be79a2c738d4c83c95c404","sha256:0a6ac333e98a500419d4263f5e1bb1534c1d319dc23566434806752168239895"],"state_sha256":"ebd68e05e241c1dbe0b3a15fe1c05fd802690488028b810127700e30daa7e536"}