{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2014:2TJRQ4Z4KXUQU3VF4Y3HHN6Z2T","short_pith_number":"pith:2TJRQ4Z4","schema_version":"1.0","canonical_sha256":"d4d318733c55e90a6ea5e63673b7d9d4c01f90cde8e494e5a9da3334d4a220f7","source":{"kind":"arxiv","id":"1406.1877","version":1},"attestation_state":"computed","paper":{"title":"Deformability-based red blood cell separation in deterministic lateral displacement devices - a simulation study","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"cond-mat.soft","authors_text":"David Holmes, Peter V. Coveney, Timm Kr\\\"uger","submitted_at":"2014-06-07T09:31:54Z","abstract_excerpt":"We show, via three-dimensional immersed-boundary-finite-element-lattice-Boltzmann simulations, that deformability-based red blood cell (RBC) separation in deterministic lateral displacement (DLD) devices is possible. This is due to the deformability-dependent lateral extension of RBCs and enables us to predict a priori which RBCs will be displaced in a given DLD geometry. Several diseases affect the deformability of human cells. Malaria-infected RBCs or sickle cells, for example, tend to become stiffer than their healthy counterparts. It is therefore desirable to design microfluidic devices wh"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1406.1877","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"cond-mat.soft","submitted_at":"2014-06-07T09:31:54Z","cross_cats_sorted":[],"title_canon_sha256":"8657837af5e15b818b4f27922948012b594b2dac2f619b9e4fc3bdec23ea62f6","abstract_canon_sha256":"55cd0ff8a68251c46b952a4ec4360ba6ff29bfe26e9398fd56700d1a67c25b28"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:19:14.425901Z","signature_b64":"GvfhqxBFrEOWa0S9Zz8iktIWJsfm2Ga1VS9T4KUcMxLl3HdiUbUatGLLHLc1LOqCH6JdDJ3zsf0M9UrR/SKIAg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"d4d318733c55e90a6ea5e63673b7d9d4c01f90cde8e494e5a9da3334d4a220f7","last_reissued_at":"2026-05-18T01:19:14.425177Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:19:14.425177Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"Deformability-based red blood cell separation in deterministic lateral displacement devices - a simulation study","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"cond-mat.soft","authors_text":"David Holmes, Peter V. Coveney, Timm Kr\\\"uger","submitted_at":"2014-06-07T09:31:54Z","abstract_excerpt":"We show, via three-dimensional immersed-boundary-finite-element-lattice-Boltzmann simulations, that deformability-based red blood cell (RBC) separation in deterministic lateral displacement (DLD) devices is possible. This is due to the deformability-dependent lateral extension of RBCs and enables us to predict a priori which RBCs will be displaced in a given DLD geometry. Several diseases affect the deformability of human cells. Malaria-infected RBCs or sickle cells, for example, tend to become stiffer than their healthy counterparts. It is therefore desirable to design microfluidic devices wh"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1406.1877","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1406.1877","created_at":"2026-05-18T01:19:14.425304+00:00"},{"alias_kind":"arxiv_version","alias_value":"1406.1877v1","created_at":"2026-05-18T01:19:14.425304+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1406.1877","created_at":"2026-05-18T01:19:14.425304+00:00"},{"alias_kind":"pith_short_12","alias_value":"2TJRQ4Z4KXUQ","created_at":"2026-05-18T12:28:11.866339+00:00"},{"alias_kind":"pith_short_16","alias_value":"2TJRQ4Z4KXUQU3VF","created_at":"2026-05-18T12:28:11.866339+00:00"},{"alias_kind":"pith_short_8","alias_value":"2TJRQ4Z4","created_at":"2026-05-18T12:28:11.866339+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/2TJRQ4Z4KXUQU3VF4Y3HHN6Z2T","json":"https://pith.science/pith/2TJRQ4Z4KXUQU3VF4Y3HHN6Z2T.json","graph_json":"https://pith.science/api/pith-number/2TJRQ4Z4KXUQU3VF4Y3HHN6Z2T/graph.json","events_json":"https://pith.science/api/pith-number/2TJRQ4Z4KXUQU3VF4Y3HHN6Z2T/events.json","paper":"https://pith.science/paper/2TJRQ4Z4"},"agent_actions":{"view_html":"https://pith.science/pith/2TJRQ4Z4KXUQU3VF4Y3HHN6Z2T","download_json":"https://pith.science/pith/2TJRQ4Z4KXUQU3VF4Y3HHN6Z2T.json","view_paper":"https://pith.science/paper/2TJRQ4Z4","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1406.1877&json=true","fetch_graph":"https://pith.science/api/pith-number/2TJRQ4Z4KXUQU3VF4Y3HHN6Z2T/graph.json","fetch_events":"https://pith.science/api/pith-number/2TJRQ4Z4KXUQU3VF4Y3HHN6Z2T/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/2TJRQ4Z4KXUQU3VF4Y3HHN6Z2T/action/timestamp_anchor","attest_storage":"https://pith.science/pith/2TJRQ4Z4KXUQU3VF4Y3HHN6Z2T/action/storage_attestation","attest_author":"https://pith.science/pith/2TJRQ4Z4KXUQU3VF4Y3HHN6Z2T/action/author_attestation","sign_citation":"https://pith.science/pith/2TJRQ4Z4KXUQU3VF4Y3HHN6Z2T/action/citation_signature","submit_replication":"https://pith.science/pith/2TJRQ4Z4KXUQU3VF4Y3HHN6Z2T/action/replication_record"}},"created_at":"2026-05-18T01:19:14.425304+00:00","updated_at":"2026-05-18T01:19:14.425304+00:00"}