{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2019:32V4TH72LGNORNG6HVDXAQ4I4K","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"dac86c568a32afac9a8a2d9662b997835bc54234660b340f8d260aa3f61b7b03","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.med-ph","submitted_at":"2019-07-15T17:26:58Z","title_canon_sha256":"4c39992553299f4cc1b66ef4bb0c1bdb77a71a2faea596f78eba49eb84ce8e06"},"schema_version":"1.0","source":{"id":"1907.06617","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1907.06617","created_at":"2026-05-17T23:40:37Z"},{"alias_kind":"arxiv_version","alias_value":"1907.06617v1","created_at":"2026-05-17T23:40:37Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1907.06617","created_at":"2026-05-17T23:40:37Z"},{"alias_kind":"pith_short_12","alias_value":"32V4TH72LGNO","created_at":"2026-05-18T12:33:07Z"},{"alias_kind":"pith_short_16","alias_value":"32V4TH72LGNORNG6","created_at":"2026-05-18T12:33:07Z"},{"alias_kind":"pith_short_8","alias_value":"32V4TH72","created_at":"2026-05-18T12:33:07Z"}],"graph_snapshots":[{"event_id":"sha256:cd0973e10a430ce292c301c74c6ff9cbd09983df8878aff5f8f22e408b541664","target":"graph","created_at":"2026-05-17T23:40:37Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"Currently, there is a high interest in Lu-177 targeted radionuclide therapies, which could be attributed to favourable results obtained from Lu-177 compounds targeting neuroendocrine and prostate tumours. Generally, it has been recognized that a transition from dosimetry based on planar images towards based on fully-quantitative SPECT is beneficial in terms of increased accuracy. SPECT based dosimetry could not only be used for achieving accurate absorbed dose per-organ, but even for deriving dose values for individual voxels. However, a voxel-wise determination of TACs is problematic since se","authors_text":"Theresa Ida G\\\"otz","cross_cats":[],"headline":"","license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.med-ph","submitted_at":"2019-07-15T17:26:58Z","title":"Technical Report: Time-Activity-Curve Integration in Lu-177 Therapies in Nuclear Medicine"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1907.06617","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:b1ec49298293ba669ebecf53b52cdcdb02b56ed04c2c53b00e8884abe747d5bb","target":"record","created_at":"2026-05-17T23:40:37Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"dac86c568a32afac9a8a2d9662b997835bc54234660b340f8d260aa3f61b7b03","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.med-ph","submitted_at":"2019-07-15T17:26:58Z","title_canon_sha256":"4c39992553299f4cc1b66ef4bb0c1bdb77a71a2faea596f78eba49eb84ce8e06"},"schema_version":"1.0","source":{"id":"1907.06617","kind":"arxiv","version":1}},"canonical_sha256":"deabc99ffa599ae8b4de3d47704388e280e6f8ecb8a8f4cbe9b2f898f0b40200","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"deabc99ffa599ae8b4de3d47704388e280e6f8ecb8a8f4cbe9b2f898f0b40200","first_computed_at":"2026-05-17T23:40:37.264529Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-17T23:40:37.264529Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"fMfrMEVHnA3g9B4iHfDqemf9qB/vlCocQN3Y1mYSq9c2VbkUCXN4xg+a8OXbH7MjpvskegiIf/0+ZzCHLcxRAA==","signature_status":"signed_v1","signed_at":"2026-05-17T23:40:37.265216Z","signed_message":"canonical_sha256_bytes"},"source_id":"1907.06617","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:b1ec49298293ba669ebecf53b52cdcdb02b56ed04c2c53b00e8884abe747d5bb","sha256:cd0973e10a430ce292c301c74c6ff9cbd09983df8878aff5f8f22e408b541664"],"state_sha256":"f0b44085634d36e750715043c7f341ca067ccef6f2c0afe28cb770ac1b0e9ed9"}