{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2025:3H5PJQ5RPZE2G4O4LIEBZVD4SW","short_pith_number":"pith:3H5PJQ5R","canonical_record":{"source":{"id":"2512.20522","kind":"arxiv","version":2},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.ins-det","submitted_at":"2025-12-23T17:12:25Z","cross_cats_sorted":[],"title_canon_sha256":"827448d4b8f686c9ff18f595ceda768633a7c9299864b7cda780d27b468d58d8","abstract_canon_sha256":"0ea54e266e6de013906737968d9bddb105376a92b7a9df8552c30c8745f62408"},"schema_version":"1.0"},"canonical_sha256":"d9faf4c3b17e49a371dc5a081cd47c9593229d0936379d7ecb90a34258dab3db","source":{"kind":"arxiv","id":"2512.20522","version":2},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2512.20522","created_at":"2026-05-20T00:05:39Z"},{"alias_kind":"arxiv_version","alias_value":"2512.20522v2","created_at":"2026-05-20T00:05:39Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2512.20522","created_at":"2026-05-20T00:05:39Z"},{"alias_kind":"pith_short_12","alias_value":"3H5PJQ5RPZE2","created_at":"2026-05-20T00:05:39Z"},{"alias_kind":"pith_short_16","alias_value":"3H5PJQ5RPZE2G4O4","created_at":"2026-05-20T00:05:39Z"},{"alias_kind":"pith_short_8","alias_value":"3H5PJQ5R","created_at":"2026-05-20T00:05:39Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2025:3H5PJQ5RPZE2G4O4LIEBZVD4SW","target":"record","payload":{"canonical_record":{"source":{"id":"2512.20522","kind":"arxiv","version":2},"metadata":{"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.ins-det","submitted_at":"2025-12-23T17:12:25Z","cross_cats_sorted":[],"title_canon_sha256":"827448d4b8f686c9ff18f595ceda768633a7c9299864b7cda780d27b468d58d8","abstract_canon_sha256":"0ea54e266e6de013906737968d9bddb105376a92b7a9df8552c30c8745f62408"},"schema_version":"1.0"},"canonical_sha256":"d9faf4c3b17e49a371dc5a081cd47c9593229d0936379d7ecb90a34258dab3db","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-20T00:05:39.704011Z","signature_b64":"YW+dlFEf8GG4iWpIntwVuhxUoPKmunTxqzZmRBtQn1Kq6s9gfbgVLGKd3BC0Ycuz1qOtlUX3n4n44DmIxnNfAg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"d9faf4c3b17e49a371dc5a081cd47c9593229d0936379d7ecb90a34258dab3db","last_reissued_at":"2026-05-20T00:05:39.703054Z","signature_status":"signed_v1","first_computed_at":"2026-05-20T00:05:39.703054Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"2512.20522","source_version":2,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-20T00:05:39Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"K7X1DyrhsukJ6rgyx2583slIb8XGYzQRa1jeVgFxqsR/XAHRszO5r7aTGxHve/F6HL8kkH95kE0BXoLNDYGoAA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-08T19:28:56.297032Z"},"content_sha256":"686b917b18a70d97baa555dd63e7460e9c8f30a2aa9cfff0874d5d87612e9bcc","schema_version":"1.0","event_id":"sha256:686b917b18a70d97baa555dd63e7460e9c8f30a2aa9cfff0874d5d87612e9bcc"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2025:3H5PJQ5RPZE2G4O4LIEBZVD4SW","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"An Instrument for Physical Vapor Deposition onto Cryo-EM Samples for Microsecond Time-Resolved Cryo-EM","license":"http://creativecommons.org/licenses/by/4.0/","headline":"","cross_cats":[],"primary_cat":"physics.ins-det","authors_text":"Axel P. Tracol Gavard, Constantin R. Kr\\\"uger, Jakub Wenz, Marcel Drabbels, Ulrich J. Lorenz, Wyatt A. Curtis","submitted_at":"2025-12-23T17:12:25Z","abstract_excerpt":"Laser flash melting and revitrification experiments have recently improved the time resolution of cryo-electron microscopy (cryo-EM) to the microsecond timescale, making it fast enough to observe many of the protein motions that are associated with function. The technique has also opened up a new dimension for cryo-EM sample preparation, making it possible to deposit compounds onto a cryo-EM sample while it is frozen, so that upon flash melting, the embedded particles experience an altered environment. For example, we have recently shown that depositing ultrathin silicon dioxide membranes onto"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2512.20522","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"integrity":{"clean":true,"summary":{"advisory":0,"critical":0,"by_detector":{},"informational":0},"endpoint":"/pith/2512.20522/integrity.json","findings":[],"available":true,"detectors_run":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938"},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-20T00:05:39Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"ztAk6ZxCAv1L3NGtECrUfGx32XZQ0k2XvwKmQTTrZOe3GdVgtJLc1+xtVIw1J3ZOj/iwuFS0+cV7J1KvuYmXBg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-08T19:28:56.297762Z"},"content_sha256":"c8a18883f2891e55095f86477647ef2875d0dbeed623a33d3fae320f34d2dca8","schema_version":"1.0","event_id":"sha256:c8a18883f2891e55095f86477647ef2875d0dbeed623a33d3fae320f34d2dca8"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/3H5PJQ5RPZE2G4O4LIEBZVD4SW/bundle.json","state_url":"https://pith.science/pith/3H5PJQ5RPZE2G4O4LIEBZVD4SW/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/3H5PJQ5RPZE2G4O4LIEBZVD4SW/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-08T19:28:56Z","links":{"resolver":"https://pith.science/pith/3H5PJQ5RPZE2G4O4LIEBZVD4SW","bundle":"https://pith.science/pith/3H5PJQ5RPZE2G4O4LIEBZVD4SW/bundle.json","state":"https://pith.science/pith/3H5PJQ5RPZE2G4O4LIEBZVD4SW/state.json","well_known_bundle":"https://pith.science/.well-known/pith/3H5PJQ5RPZE2G4O4LIEBZVD4SW/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2025:3H5PJQ5RPZE2G4O4LIEBZVD4SW","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"0ea54e266e6de013906737968d9bddb105376a92b7a9df8552c30c8745f62408","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.ins-det","submitted_at":"2025-12-23T17:12:25Z","title_canon_sha256":"827448d4b8f686c9ff18f595ceda768633a7c9299864b7cda780d27b468d58d8"},"schema_version":"1.0","source":{"id":"2512.20522","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"2512.20522","created_at":"2026-05-20T00:05:39Z"},{"alias_kind":"arxiv_version","alias_value":"2512.20522v2","created_at":"2026-05-20T00:05:39Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.2512.20522","created_at":"2026-05-20T00:05:39Z"},{"alias_kind":"pith_short_12","alias_value":"3H5PJQ5RPZE2","created_at":"2026-05-20T00:05:39Z"},{"alias_kind":"pith_short_16","alias_value":"3H5PJQ5RPZE2G4O4","created_at":"2026-05-20T00:05:39Z"},{"alias_kind":"pith_short_8","alias_value":"3H5PJQ5R","created_at":"2026-05-20T00:05:39Z"}],"graph_snapshots":[{"event_id":"sha256:c8a18883f2891e55095f86477647ef2875d0dbeed623a33d3fae320f34d2dca8","target":"graph","created_at":"2026-05-20T00:05:39Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"integrity":{"available":true,"clean":true,"detectors_run":[],"endpoint":"/pith/2512.20522/integrity.json","findings":[],"snapshot_sha256":"c28c3603d3b5d939e8dc4c7e95fa8dfce3d595e45f758748cecf8e644a296938","summary":{"advisory":0,"by_detector":{},"critical":0,"informational":0}},"paper":{"abstract_excerpt":"Laser flash melting and revitrification experiments have recently improved the time resolution of cryo-electron microscopy (cryo-EM) to the microsecond timescale, making it fast enough to observe many of the protein motions that are associated with function. The technique has also opened up a new dimension for cryo-EM sample preparation, making it possible to deposit compounds onto a cryo-EM sample while it is frozen, so that upon flash melting, the embedded particles experience an altered environment. For example, we have recently shown that depositing ultrathin silicon dioxide membranes onto","authors_text":"Axel P. Tracol Gavard, Constantin R. Kr\\\"uger, Jakub Wenz, Marcel Drabbels, Ulrich J. Lorenz, Wyatt A. Curtis","cross_cats":[],"headline":"","license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.ins-det","submitted_at":"2025-12-23T17:12:25Z","title":"An Instrument for Physical Vapor Deposition onto Cryo-EM Samples for Microsecond Time-Resolved Cryo-EM"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"2512.20522","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:686b917b18a70d97baa555dd63e7460e9c8f30a2aa9cfff0874d5d87612e9bcc","target":"record","created_at":"2026-05-20T00:05:39Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"0ea54e266e6de013906737968d9bddb105376a92b7a9df8552c30c8745f62408","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by/4.0/","primary_cat":"physics.ins-det","submitted_at":"2025-12-23T17:12:25Z","title_canon_sha256":"827448d4b8f686c9ff18f595ceda768633a7c9299864b7cda780d27b468d58d8"},"schema_version":"1.0","source":{"id":"2512.20522","kind":"arxiv","version":2}},"canonical_sha256":"d9faf4c3b17e49a371dc5a081cd47c9593229d0936379d7ecb90a34258dab3db","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"d9faf4c3b17e49a371dc5a081cd47c9593229d0936379d7ecb90a34258dab3db","first_computed_at":"2026-05-20T00:05:39.703054Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-20T00:05:39.703054Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"YW+dlFEf8GG4iWpIntwVuhxUoPKmunTxqzZmRBtQn1Kq6s9gfbgVLGKd3BC0Ycuz1qOtlUX3n4n44DmIxnNfAg==","signature_status":"signed_v1","signed_at":"2026-05-20T00:05:39.704011Z","signed_message":"canonical_sha256_bytes"},"source_id":"2512.20522","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:686b917b18a70d97baa555dd63e7460e9c8f30a2aa9cfff0874d5d87612e9bcc","sha256:c8a18883f2891e55095f86477647ef2875d0dbeed623a33d3fae320f34d2dca8"],"state_sha256":"fa6c435017a5821636914366ea7517f1e89677aaaac0c6df3adedddd737eb2db"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"nli8JGxtk+QR2BjSdPkBv1+dN95k7VpjVYCLseV3EYbdCqDvhmaCoVh23S9i3L5glqixw7bKY8haXUz/Af3pBg==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-08T19:28:56.302643Z","bundle_sha256":"7558bf256447e0ef08b585b29428e9eca846277fb61919c60738a3bd11324345"}}