{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2016:3LATHGO46EET255RHAT24FWMBG","short_pith_number":"pith:3LATHGO4","canonical_record":{"source":{"id":"1608.02976","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2016-08-09T20:15:02Z","cross_cats_sorted":[],"title_canon_sha256":"af30d754722f634668062f761a0822ce4acb889a5549fe74950a37b4e4f9e766","abstract_canon_sha256":"7d8b4d7d0e3030972140b1fd7bcc6730b80de1b3ebe447988da11423cedbe3c5"},"schema_version":"1.0"},"canonical_sha256":"dac13399dcf1093d77b13827ae16cc09a1ffb5a2aa445f99e26206f31c4f53af","source":{"kind":"arxiv","id":"1608.02976","version":2},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1608.02976","created_at":"2026-05-18T01:00:05Z"},{"alias_kind":"arxiv_version","alias_value":"1608.02976v2","created_at":"2026-05-18T01:00:05Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1608.02976","created_at":"2026-05-18T01:00:05Z"},{"alias_kind":"pith_short_12","alias_value":"3LATHGO46EET","created_at":"2026-05-18T12:29:55Z"},{"alias_kind":"pith_short_16","alias_value":"3LATHGO46EET255R","created_at":"2026-05-18T12:29:55Z"},{"alias_kind":"pith_short_8","alias_value":"3LATHGO4","created_at":"2026-05-18T12:29:55Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2016:3LATHGO46EET255RHAT24FWMBG","target":"record","payload":{"canonical_record":{"source":{"id":"1608.02976","kind":"arxiv","version":2},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2016-08-09T20:15:02Z","cross_cats_sorted":[],"title_canon_sha256":"af30d754722f634668062f761a0822ce4acb889a5549fe74950a37b4e4f9e766","abstract_canon_sha256":"7d8b4d7d0e3030972140b1fd7bcc6730b80de1b3ebe447988da11423cedbe3c5"},"schema_version":"1.0"},"canonical_sha256":"dac13399dcf1093d77b13827ae16cc09a1ffb5a2aa445f99e26206f31c4f53af","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T01:00:05.492182Z","signature_b64":"Eo0+vDqcIeOCUuv5pTBRswvigHxPXdnAn7o2h0sA7YB3Edg5Y2gP21nuuFZfnDeT61rAlFM4GXszhzXAoSPBDA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"dac13399dcf1093d77b13827ae16cc09a1ffb5a2aa445f99e26206f31c4f53af","last_reissued_at":"2026-05-18T01:00:05.491761Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T01:00:05.491761Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1608.02976","source_version":2,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:00:05Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"K5H5MiPPsQB4FNa703UAvJHZpPT3/3q9CQ1PdZz90FdwqVauyJe4SH2mBtGr94oZsJ1SK1detWaFb5Z+2F8+Dg==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-27T23:13:27.368038Z"},"content_sha256":"f0bb5a5809a67219a43b988177411badb01a195c378e3f1257698be311bd8863","schema_version":"1.0","event_id":"sha256:f0bb5a5809a67219a43b988177411badb01a195c378e3f1257698be311bd8863"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2016:3LATHGO46EET255RHAT24FWMBG","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"A comparison of the innate flexibilities of six chains in F$_1$-ATPase with identical secondary and tertiary folds; 3 active enzymes and 3 structural proteins","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.BM","authors_text":"Monique M. Tirion","submitted_at":"2016-08-09T20:15:02Z","abstract_excerpt":"The $\\alpha$ and $\\beta$ subunits comprising the hexameric assembly of F1-ATPase share a high degree of structural identity, though low primary identity. Each subunit binds nucleotide in similar pockets, yet only $\\beta$ subunits are catalytically active. Why? We re-examine their internal symmetry axes and observe interesting differences. Dividing each chain into an N-terminal head region, a C-terminal foot region, and a central torso, we observe (1) that while the foot and head regions in all chains obtain high and similar mobility, the torsos obtain different mobility profiles, with the $\\be"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1608.02976","kind":"arxiv","version":2},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T01:00:05Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"t5F1iP/coDvcC4KOidj0zyr5/Rcd9dzpDhaMaT5pZldfzWS5f6SoAz86RqTAJX0HJFGZqfsc3nhs+GT6bcXXDA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-27T23:13:27.368731Z"},"content_sha256":"6336c3a88afbf7ac20769a9ee1a1eafba6b27f8cdf5358efc77536f43b780bf8","schema_version":"1.0","event_id":"sha256:6336c3a88afbf7ac20769a9ee1a1eafba6b27f8cdf5358efc77536f43b780bf8"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/3LATHGO46EET255RHAT24FWMBG/bundle.json","state_url":"https://pith.science/pith/3LATHGO46EET255RHAT24FWMBG/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/3LATHGO46EET255RHAT24FWMBG/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-27T23:13:27Z","links":{"resolver":"https://pith.science/pith/3LATHGO46EET255RHAT24FWMBG","bundle":"https://pith.science/pith/3LATHGO46EET255RHAT24FWMBG/bundle.json","state":"https://pith.science/pith/3LATHGO46EET255RHAT24FWMBG/state.json","well_known_bundle":"https://pith.science/.well-known/pith/3LATHGO46EET255RHAT24FWMBG/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2016:3LATHGO46EET255RHAT24FWMBG","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"7d8b4d7d0e3030972140b1fd7bcc6730b80de1b3ebe447988da11423cedbe3c5","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2016-08-09T20:15:02Z","title_canon_sha256":"af30d754722f634668062f761a0822ce4acb889a5549fe74950a37b4e4f9e766"},"schema_version":"1.0","source":{"id":"1608.02976","kind":"arxiv","version":2}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1608.02976","created_at":"2026-05-18T01:00:05Z"},{"alias_kind":"arxiv_version","alias_value":"1608.02976v2","created_at":"2026-05-18T01:00:05Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1608.02976","created_at":"2026-05-18T01:00:05Z"},{"alias_kind":"pith_short_12","alias_value":"3LATHGO46EET","created_at":"2026-05-18T12:29:55Z"},{"alias_kind":"pith_short_16","alias_value":"3LATHGO46EET255R","created_at":"2026-05-18T12:29:55Z"},{"alias_kind":"pith_short_8","alias_value":"3LATHGO4","created_at":"2026-05-18T12:29:55Z"}],"graph_snapshots":[{"event_id":"sha256:6336c3a88afbf7ac20769a9ee1a1eafba6b27f8cdf5358efc77536f43b780bf8","target":"graph","created_at":"2026-05-18T01:00:05Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"The $\\alpha$ and $\\beta$ subunits comprising the hexameric assembly of F1-ATPase share a high degree of structural identity, though low primary identity. Each subunit binds nucleotide in similar pockets, yet only $\\beta$ subunits are catalytically active. Why? We re-examine their internal symmetry axes and observe interesting differences. Dividing each chain into an N-terminal head region, a C-terminal foot region, and a central torso, we observe (1) that while the foot and head regions in all chains obtain high and similar mobility, the torsos obtain different mobility profiles, with the $\\be","authors_text":"Monique M. Tirion","cross_cats":[],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2016-08-09T20:15:02Z","title":"A comparison of the innate flexibilities of six chains in F$_1$-ATPase with identical secondary and tertiary folds; 3 active enzymes and 3 structural proteins"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1608.02976","kind":"arxiv","version":2},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:f0bb5a5809a67219a43b988177411badb01a195c378e3f1257698be311bd8863","target":"record","created_at":"2026-05-18T01:00:05Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"7d8b4d7d0e3030972140b1fd7bcc6730b80de1b3ebe447988da11423cedbe3c5","cross_cats_sorted":[],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.BM","submitted_at":"2016-08-09T20:15:02Z","title_canon_sha256":"af30d754722f634668062f761a0822ce4acb889a5549fe74950a37b4e4f9e766"},"schema_version":"1.0","source":{"id":"1608.02976","kind":"arxiv","version":2}},"canonical_sha256":"dac13399dcf1093d77b13827ae16cc09a1ffb5a2aa445f99e26206f31c4f53af","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"dac13399dcf1093d77b13827ae16cc09a1ffb5a2aa445f99e26206f31c4f53af","first_computed_at":"2026-05-18T01:00:05.491761Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T01:00:05.491761Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"Eo0+vDqcIeOCUuv5pTBRswvigHxPXdnAn7o2h0sA7YB3Edg5Y2gP21nuuFZfnDeT61rAlFM4GXszhzXAoSPBDA==","signature_status":"signed_v1","signed_at":"2026-05-18T01:00:05.492182Z","signed_message":"canonical_sha256_bytes"},"source_id":"1608.02976","source_kind":"arxiv","source_version":2}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:f0bb5a5809a67219a43b988177411badb01a195c378e3f1257698be311bd8863","sha256:6336c3a88afbf7ac20769a9ee1a1eafba6b27f8cdf5358efc77536f43b780bf8"],"state_sha256":"c2ad80ff7d0f86347ce910f172e9e7bcefaab2ebefc99f6e100ce3129be371ec"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"T5RXTi7tsARoqwiuSH7vUR+6gapikyPfZwE14rX1EJEWPdcSkqrZ/dCD2CY0LM3Z4gBh5o7KVkexsZTJnfoSCA==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-27T23:13:27.372345Z","bundle_sha256":"59cf86ba28dbd8aa994d909e7907dc3f6ae2bd801ced4731a4134929652fd44f"}}