{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2010:3R5ZN74NKPYR7M4CZ573QMUUUS","short_pith_number":"pith:3R5ZN74N","canonical_record":{"source":{"id":"1012.3437","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by-nc-sa/3.0/","primary_cat":"q-bio.OT","submitted_at":"2010-12-15T19:41:49Z","cross_cats_sorted":[],"title_canon_sha256":"30b3f99884d110e0d6f24e11941b364cb7064e044139e6baeac73db05dc30aae","abstract_canon_sha256":"b0d18f626d56210bd41e6026032a3e6081d6cc3aeef893ae033c48603cd4c4bb"},"schema_version":"1.0"},"canonical_sha256":"dc7b96ff8d53f11fb382cf7fb83294a49a74eb5f2305c3d75b5de42c45129332","source":{"kind":"arxiv","id":"1012.3437","version":1},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1012.3437","created_at":"2026-05-18T04:33:16Z"},{"alias_kind":"arxiv_version","alias_value":"1012.3437v1","created_at":"2026-05-18T04:33:16Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1012.3437","created_at":"2026-05-18T04:33:16Z"},{"alias_kind":"pith_short_12","alias_value":"3R5ZN74NKPYR","created_at":"2026-05-18T12:26:03Z"},{"alias_kind":"pith_short_16","alias_value":"3R5ZN74NKPYR7M4C","created_at":"2026-05-18T12:26:03Z"},{"alias_kind":"pith_short_8","alias_value":"3R5ZN74N","created_at":"2026-05-18T12:26:03Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2010:3R5ZN74NKPYR7M4CZ573QMUUUS","target":"record","payload":{"canonical_record":{"source":{"id":"1012.3437","kind":"arxiv","version":1},"metadata":{"license":"http://creativecommons.org/licenses/by-nc-sa/3.0/","primary_cat":"q-bio.OT","submitted_at":"2010-12-15T19:41:49Z","cross_cats_sorted":[],"title_canon_sha256":"30b3f99884d110e0d6f24e11941b364cb7064e044139e6baeac73db05dc30aae","abstract_canon_sha256":"b0d18f626d56210bd41e6026032a3e6081d6cc3aeef893ae033c48603cd4c4bb"},"schema_version":"1.0"},"canonical_sha256":"dc7b96ff8d53f11fb382cf7fb83294a49a74eb5f2305c3d75b5de42c45129332","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T04:33:16.813262Z","signature_b64":"lOMqwjOaGTPov8717vs7G3KI2WWIplKZ7rx3aaxJHlPF+oB5kRndd+Sbcyz3200Cd4iKXSx0AY2T14GUfZ3fDg==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"dc7b96ff8d53f11fb382cf7fb83294a49a74eb5f2305c3d75b5de42c45129332","last_reissued_at":"2026-05-18T04:33:16.812657Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T04:33:16.812657Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1012.3437","source_version":1,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T04:33:16Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"46WRlwtlLQMJxBGjYWoMK6lxUZbtZCuV50fvIBvEw3hhYc99XmR85PtTnDVUDoStfzGYC4/oWa219Bn3tujDDA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-27T15:01:54.026600Z"},"content_sha256":"b7daa318bdd776a1913e65bca642975031f282adf7f29e5368408b5172383378","schema_version":"1.0","event_id":"sha256:b7daa318bdd776a1913e65bca642975031f282adf7f29e5368408b5172383378"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2010:3R5ZN74NKPYR7M4CZ573QMUUUS","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"The Virtual Institute for Integrative Biology (VIIB)","license":"http://creativecommons.org/licenses/by-nc-sa/3.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.OT","authors_text":"David S. Holmes, Fernando Gonz\\'alez-Nilo, Gustavo Rivera, Raul Isea, Tom\\'as Perez-Acle","submitted_at":"2010-12-15T19:41:49Z","abstract_excerpt":"The Virtual Institute for Integrative Biology (VIIB) is a Latin American initiative for achieving global collaborative e-Science in the areas of bioinformatics, genome biology, systems biology, metagenomics, medical applications and nanobiotechnolgy. The scientific agenda of VIIB includes: construction of databases for comparative genomics, the AlterORF database for alternate open reading frames discovery in genomes, bioinformatics services and protein simulations for biotechnological and medical applications. Human resource development has been promoted through co-sponsored students and share"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1012.3437","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T04:33:16Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"Tzu7pNpgDXULTiPD/JSIkXV1DGhYYCDY6XRsLFperHSN4Q5XOKrgg9IEahTFJgcvOqZxow4zBJQGJIdR6lhEDA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-05-27T15:01:54.027228Z"},"content_sha256":"ffd098b37d73526cbc5f398b4a09c47270e7900fba60e48b49bdca0576dbfcde","schema_version":"1.0","event_id":"sha256:ffd098b37d73526cbc5f398b4a09c47270e7900fba60e48b49bdca0576dbfcde"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/3R5ZN74NKPYR7M4CZ573QMUUUS/bundle.json","state_url":"https://pith.science/pith/3R5ZN74NKPYR7M4CZ573QMUUUS/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/3R5ZN74NKPYR7M4CZ573QMUUUS/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-05-27T15:01:54Z","links":{"resolver":"https://pith.science/pith/3R5ZN74NKPYR7M4CZ573QMUUUS","bundle":"https://pith.science/pith/3R5ZN74NKPYR7M4CZ573QMUUUS/bundle.json","state":"https://pith.science/pith/3R5ZN74NKPYR7M4CZ573QMUUUS/state.json","well_known_bundle":"https://pith.science/.well-known/pith/3R5ZN74NKPYR7M4CZ573QMUUUS/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2010:3R5ZN74NKPYR7M4CZ573QMUUUS","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"b0d18f626d56210bd41e6026032a3e6081d6cc3aeef893ae033c48603cd4c4bb","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by-nc-sa/3.0/","primary_cat":"q-bio.OT","submitted_at":"2010-12-15T19:41:49Z","title_canon_sha256":"30b3f99884d110e0d6f24e11941b364cb7064e044139e6baeac73db05dc30aae"},"schema_version":"1.0","source":{"id":"1012.3437","kind":"arxiv","version":1}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1012.3437","created_at":"2026-05-18T04:33:16Z"},{"alias_kind":"arxiv_version","alias_value":"1012.3437v1","created_at":"2026-05-18T04:33:16Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1012.3437","created_at":"2026-05-18T04:33:16Z"},{"alias_kind":"pith_short_12","alias_value":"3R5ZN74NKPYR","created_at":"2026-05-18T12:26:03Z"},{"alias_kind":"pith_short_16","alias_value":"3R5ZN74NKPYR7M4C","created_at":"2026-05-18T12:26:03Z"},{"alias_kind":"pith_short_8","alias_value":"3R5ZN74N","created_at":"2026-05-18T12:26:03Z"}],"graph_snapshots":[{"event_id":"sha256:ffd098b37d73526cbc5f398b4a09c47270e7900fba60e48b49bdca0576dbfcde","target":"graph","created_at":"2026-05-18T04:33:16Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"The Virtual Institute for Integrative Biology (VIIB) is a Latin American initiative for achieving global collaborative e-Science in the areas of bioinformatics, genome biology, systems biology, metagenomics, medical applications and nanobiotechnolgy. The scientific agenda of VIIB includes: construction of databases for comparative genomics, the AlterORF database for alternate open reading frames discovery in genomes, bioinformatics services and protein simulations for biotechnological and medical applications. Human resource development has been promoted through co-sponsored students and share","authors_text":"David S. Holmes, Fernando Gonz\\'alez-Nilo, Gustavo Rivera, Raul Isea, Tom\\'as Perez-Acle","cross_cats":[],"headline":"","license":"http://creativecommons.org/licenses/by-nc-sa/3.0/","primary_cat":"q-bio.OT","submitted_at":"2010-12-15T19:41:49Z","title":"The Virtual Institute for Integrative Biology (VIIB)"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1012.3437","kind":"arxiv","version":1},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:b7daa318bdd776a1913e65bca642975031f282adf7f29e5368408b5172383378","target":"record","created_at":"2026-05-18T04:33:16Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"b0d18f626d56210bd41e6026032a3e6081d6cc3aeef893ae033c48603cd4c4bb","cross_cats_sorted":[],"license":"http://creativecommons.org/licenses/by-nc-sa/3.0/","primary_cat":"q-bio.OT","submitted_at":"2010-12-15T19:41:49Z","title_canon_sha256":"30b3f99884d110e0d6f24e11941b364cb7064e044139e6baeac73db05dc30aae"},"schema_version":"1.0","source":{"id":"1012.3437","kind":"arxiv","version":1}},"canonical_sha256":"dc7b96ff8d53f11fb382cf7fb83294a49a74eb5f2305c3d75b5de42c45129332","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"dc7b96ff8d53f11fb382cf7fb83294a49a74eb5f2305c3d75b5de42c45129332","first_computed_at":"2026-05-18T04:33:16.812657Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T04:33:16.812657Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"lOMqwjOaGTPov8717vs7G3KI2WWIplKZ7rx3aaxJHlPF+oB5kRndd+Sbcyz3200Cd4iKXSx0AY2T14GUfZ3fDg==","signature_status":"signed_v1","signed_at":"2026-05-18T04:33:16.813262Z","signed_message":"canonical_sha256_bytes"},"source_id":"1012.3437","source_kind":"arxiv","source_version":1}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:b7daa318bdd776a1913e65bca642975031f282adf7f29e5368408b5172383378","sha256:ffd098b37d73526cbc5f398b4a09c47270e7900fba60e48b49bdca0576dbfcde"],"state_sha256":"509dbb7023b3c0205b02f0c91b7f8f9c9e6fe53b6a1546c59ee5974ad1415b8c"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"RlRPgi76qDmD+u5jteJqdTafAban0BVMkcU9sjUdHQVLHYHP4A9aJ6J7JZhVwlPJlPW5/I44CsIuqHBuUeyBAw==","signed_message":"bundle_sha256_bytes","signed_at":"2026-05-27T15:01:54.030467Z","bundle_sha256":"95f298867b1a131d67be31a87b7037aa22086352386f1b97e3749a437c305f50"}}