{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2014:3SBZPIO4MLKNVPYNVA7O44HXCD","short_pith_number":"pith:3SBZPIO4","schema_version":"1.0","canonical_sha256":"dc8397a1dc62d4dabf0da83eee70f710dddacdc284e7da20511044340e8e9409","source":{"kind":"arxiv","id":"1412.3441","version":1},"attestation_state":"computed","paper":{"title":"A Stochastic Model for the Normal Tissue Complication Probability (NTCP) in Radiation Treatment of Cancer","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.TO","authors_text":"Jiafen Gong, Martin Burger, Theresa Stocks, Thomas Hillen","submitted_at":"2014-12-10T20:32:38Z","abstract_excerpt":"The normal tissue complication probability (NTCP) is a measure for the estimated side effects of a given radiation treatment schedule. Here we use a stochastic logistic birth death process to define an organ specific and patient specific NTCP. We emphasise an asymptotic simplification which relates the NTCP to the solution of a logistic differential equation. This framework allows for a direct use of the NTCP model in clinical practice. We formulate, but do not solve, related optimization problems."},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1412.3441","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.TO","submitted_at":"2014-12-10T20:32:38Z","cross_cats_sorted":[],"title_canon_sha256":"4b14e50c6aca36430cbb3e5551e539daf9775c7e91a477320d9407f88bcc0bab","abstract_canon_sha256":"146b8adf5529dc6c23cab077f96b86566625afd0331c6f654452ffcbafe43b3b"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T02:31:36.714575Z","signature_b64":"dM7DvSvTGB2wS4X3mElmEsY0BeSAs/1ktsqWkJeqjNgGtH6yVzpnMnlsNU5HmyTZm8LcuLAjkGxMqsiM17ACCA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"dc8397a1dc62d4dabf0da83eee70f710dddacdc284e7da20511044340e8e9409","last_reissued_at":"2026-05-18T02:31:36.713913Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T02:31:36.713913Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"A Stochastic Model for the Normal Tissue Complication Probability (NTCP) in Radiation Treatment of Cancer","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":[],"primary_cat":"q-bio.TO","authors_text":"Jiafen Gong, Martin Burger, Theresa Stocks, Thomas Hillen","submitted_at":"2014-12-10T20:32:38Z","abstract_excerpt":"The normal tissue complication probability (NTCP) is a measure for the estimated side effects of a given radiation treatment schedule. Here we use a stochastic logistic birth death process to define an organ specific and patient specific NTCP. We emphasise an asymptotic simplification which relates the NTCP to the solution of a logistic differential equation. This framework allows for a direct use of the NTCP model in clinical practice. We formulate, but do not solve, related optimization problems."},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1412.3441","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1412.3441","created_at":"2026-05-18T02:31:36.714027+00:00"},{"alias_kind":"arxiv_version","alias_value":"1412.3441v1","created_at":"2026-05-18T02:31:36.714027+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1412.3441","created_at":"2026-05-18T02:31:36.714027+00:00"},{"alias_kind":"pith_short_12","alias_value":"3SBZPIO4MLKN","created_at":"2026-05-18T12:28:11.866339+00:00"},{"alias_kind":"pith_short_16","alias_value":"3SBZPIO4MLKNVPYN","created_at":"2026-05-18T12:28:11.866339+00:00"},{"alias_kind":"pith_short_8","alias_value":"3SBZPIO4","created_at":"2026-05-18T12:28:11.866339+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/3SBZPIO4MLKNVPYNVA7O44HXCD","json":"https://pith.science/pith/3SBZPIO4MLKNVPYNVA7O44HXCD.json","graph_json":"https://pith.science/api/pith-number/3SBZPIO4MLKNVPYNVA7O44HXCD/graph.json","events_json":"https://pith.science/api/pith-number/3SBZPIO4MLKNVPYNVA7O44HXCD/events.json","paper":"https://pith.science/paper/3SBZPIO4"},"agent_actions":{"view_html":"https://pith.science/pith/3SBZPIO4MLKNVPYNVA7O44HXCD","download_json":"https://pith.science/pith/3SBZPIO4MLKNVPYNVA7O44HXCD.json","view_paper":"https://pith.science/paper/3SBZPIO4","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1412.3441&json=true","fetch_graph":"https://pith.science/api/pith-number/3SBZPIO4MLKNVPYNVA7O44HXCD/graph.json","fetch_events":"https://pith.science/api/pith-number/3SBZPIO4MLKNVPYNVA7O44HXCD/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/3SBZPIO4MLKNVPYNVA7O44HXCD/action/timestamp_anchor","attest_storage":"https://pith.science/pith/3SBZPIO4MLKNVPYNVA7O44HXCD/action/storage_attestation","attest_author":"https://pith.science/pith/3SBZPIO4MLKNVPYNVA7O44HXCD/action/author_attestation","sign_citation":"https://pith.science/pith/3SBZPIO4MLKNVPYNVA7O44HXCD/action/citation_signature","submit_replication":"https://pith.science/pith/3SBZPIO4MLKNVPYNVA7O44HXCD/action/replication_record"}},"created_at":"2026-05-18T02:31:36.714027+00:00","updated_at":"2026-05-18T02:31:36.714027+00:00"}