{"bundle_type":"pith_open_graph_bundle","bundle_version":"1.0","pith_number":"pith:2018:3UGOZRDJMUWWI7TPEWF2YSLBKX","short_pith_number":"pith:3UGOZRDJ","canonical_record":{"source":{"id":"1804.11005","kind":"arxiv","version":3},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.MN","submitted_at":"2018-04-29T23:40:44Z","cross_cats_sorted":["cs.IT","math.IT","q-bio.QM","stat.AP","stat.ML"],"title_canon_sha256":"7fdaa741360e9d80bc860b03b8392a0a3ea43940a711bc5388d7cae814a5c27a","abstract_canon_sha256":"8951273621febbd0be17bf1efefc585ab71766f448badaa0df2ec82e2a43d6f6"},"schema_version":"1.0"},"canonical_sha256":"dd0cecc469652d647e6f258bac496155d041228dd8706aafcd76049151973da4","source":{"kind":"arxiv","id":"1804.11005","version":3},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1804.11005","created_at":"2026-05-18T00:01:38Z"},{"alias_kind":"arxiv_version","alias_value":"1804.11005v3","created_at":"2026-05-18T00:01:38Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1804.11005","created_at":"2026-05-18T00:01:38Z"},{"alias_kind":"pith_short_12","alias_value":"3UGOZRDJMUWW","created_at":"2026-05-18T12:32:05Z"},{"alias_kind":"pith_short_16","alias_value":"3UGOZRDJMUWWI7TP","created_at":"2026-05-18T12:32:05Z"},{"alias_kind":"pith_short_8","alias_value":"3UGOZRDJ","created_at":"2026-05-18T12:32:05Z"}],"events":[{"event_type":"record_created","subject_pith_number":"pith:2018:3UGOZRDJMUWWI7TPEWF2YSLBKX","target":"record","payload":{"canonical_record":{"source":{"id":"1804.11005","kind":"arxiv","version":3},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.MN","submitted_at":"2018-04-29T23:40:44Z","cross_cats_sorted":["cs.IT","math.IT","q-bio.QM","stat.AP","stat.ML"],"title_canon_sha256":"7fdaa741360e9d80bc860b03b8392a0a3ea43940a711bc5388d7cae814a5c27a","abstract_canon_sha256":"8951273621febbd0be17bf1efefc585ab71766f448badaa0df2ec82e2a43d6f6"},"schema_version":"1.0"},"canonical_sha256":"dd0cecc469652d647e6f258bac496155d041228dd8706aafcd76049151973da4","receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T00:01:38.470742Z","signature_b64":"88chK9zLKTC6Vcyjs+eENGVTdl3D7vuYeZd1bu2gywXzHboVgWoi4gOuzbiCr0gwMMot04nAutrSN3/WucOpDw==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"dd0cecc469652d647e6f258bac496155d041228dd8706aafcd76049151973da4","last_reissued_at":"2026-05-18T00:01:38.470143Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T00:01:38.470143Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"source_kind":"arxiv","source_id":"1804.11005","source_version":3,"attestation_state":"computed"},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T00:01:38Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"dc0fNwitcOMwUodEfEjoAD5a2td7kD9Oq5Ev35vVp1tuLzDnSMSOQP5VMMbWImu1Ox9t6iVqp8a3MMZHdumJAA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-22T02:34:54.629429Z"},"content_sha256":"5592605b38263c56e658b9a228f636dea234556665e5a07622c5e52fa726eb47","schema_version":"1.0","event_id":"sha256:5592605b38263c56e658b9a228f636dea234556665e5a07622c5e52fa726eb47"},{"event_type":"graph_snapshot","subject_pith_number":"pith:2018:3UGOZRDJMUWWI7TPEWF2YSLBKX","target":"graph","payload":{"graph_snapshot":{"paper":{"title":"Building Models for Biopathway Dynamics Using Intrinsic Dimensionality Analysis","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["cs.IT","math.IT","q-bio.QM","stat.AP","stat.ML"],"primary_cat":"q-bio.MN","authors_text":"Emilia M. Wysocka, Laura Condon, Sahil Garg, Tirthankar Bandyopadhyay, Valery Dzutsati","submitted_at":"2018-04-29T23:40:44Z","abstract_excerpt":"An important task for many if not all the scientific domains is efficient knowledge integration, testing and codification. It is often solved with model construction in a controllable computational environment. In spite of that, the throughput of in-silico simulation-based observations become similarly intractable for thorough analysis. This is especially the case in molecular biology, which served as a subject for this study. In this project, we aimed to test some approaches developed to deal with the curse of dimensionality. Among these we found dimension reduction techniques especially appe"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1804.11005","kind":"arxiv","version":3},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"verdict_id":null},"signer":{"signer_id":"pith.science","signer_type":"pith_registry","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"created_at":"2026-05-18T00:01:38Z","supersedes":[],"prev_event":null,"signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"XA3d/5/2Jfde5tLYHPRLf3gSTzLoTesm3AZg46sP8AiNpFq9ELQ1zVoQ8Es7eoQcNHZt1nV/Ha+WapKWAZglBA==","signed_message":"open_graph_event_sha256_bytes","signed_at":"2026-06-22T02:34:54.629781Z"},"content_sha256":"6481017c7e957edc3d0a27fc6b8cbfeafc74b1638caac45e6dcb129461eff088","schema_version":"1.0","event_id":"sha256:6481017c7e957edc3d0a27fc6b8cbfeafc74b1638caac45e6dcb129461eff088"}],"timestamp_proofs":[],"mirror_hints":[{"mirror_type":"https","name":"Pith Resolver","base_url":"https://pith.science","bundle_url":"https://pith.science/pith/3UGOZRDJMUWWI7TPEWF2YSLBKX/bundle.json","state_url":"https://pith.science/pith/3UGOZRDJMUWWI7TPEWF2YSLBKX/state.json","well_known_bundle_url":"https://pith.science/.well-known/pith/3UGOZRDJMUWWI7TPEWF2YSLBKX/bundle.json","status":"primary"}],"public_keys":[{"key_id":"pith-v1-2026-05","algorithm":"ed25519","format":"raw","public_key_b64":"stVStoiQhXFxp4s2pdzPNoqVNBMojDU/fJ2db5S3CbM=","public_key_hex":"b2d552b68890857171a78b36a5dccf368a953413288c353f7c9d9d6f94b709b3","fingerprint_sha256_b32_first128bits":"RVFV5Z2OI2J3ZUO7ERDEBCYNKS","fingerprint_sha256_hex":"8d4b5ee74e4693bcd1df2446408b0d54","rotates_at":null,"url":"https://pith.science/pith-signing-key.json","notes":"Pith uses this Ed25519 key to sign canonical record SHA-256 digests. Verify with: ed25519_verify(public_key, message=canonical_sha256_bytes, signature=base64decode(signature_b64))."}],"merge_version":"pith-open-graph-merge-v1","built_at":"2026-06-22T02:34:54Z","links":{"resolver":"https://pith.science/pith/3UGOZRDJMUWWI7TPEWF2YSLBKX","bundle":"https://pith.science/pith/3UGOZRDJMUWWI7TPEWF2YSLBKX/bundle.json","state":"https://pith.science/pith/3UGOZRDJMUWWI7TPEWF2YSLBKX/state.json","well_known_bundle":"https://pith.science/.well-known/pith/3UGOZRDJMUWWI7TPEWF2YSLBKX/bundle.json"},"state":{"state_type":"pith_open_graph_state","state_version":"1.0","pith_number":"pith:2018:3UGOZRDJMUWWI7TPEWF2YSLBKX","merge_version":"pith-open-graph-merge-v1","event_count":2,"valid_event_count":2,"invalid_event_count":0,"equivocation_count":0,"current":{"canonical_record":{"metadata":{"abstract_canon_sha256":"8951273621febbd0be17bf1efefc585ab71766f448badaa0df2ec82e2a43d6f6","cross_cats_sorted":["cs.IT","math.IT","q-bio.QM","stat.AP","stat.ML"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.MN","submitted_at":"2018-04-29T23:40:44Z","title_canon_sha256":"7fdaa741360e9d80bc860b03b8392a0a3ea43940a711bc5388d7cae814a5c27a"},"schema_version":"1.0","source":{"id":"1804.11005","kind":"arxiv","version":3}},"source_aliases":[{"alias_kind":"arxiv","alias_value":"1804.11005","created_at":"2026-05-18T00:01:38Z"},{"alias_kind":"arxiv_version","alias_value":"1804.11005v3","created_at":"2026-05-18T00:01:38Z"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1804.11005","created_at":"2026-05-18T00:01:38Z"},{"alias_kind":"pith_short_12","alias_value":"3UGOZRDJMUWW","created_at":"2026-05-18T12:32:05Z"},{"alias_kind":"pith_short_16","alias_value":"3UGOZRDJMUWWI7TP","created_at":"2026-05-18T12:32:05Z"},{"alias_kind":"pith_short_8","alias_value":"3UGOZRDJ","created_at":"2026-05-18T12:32:05Z"}],"graph_snapshots":[{"event_id":"sha256:6481017c7e957edc3d0a27fc6b8cbfeafc74b1638caac45e6dcb129461eff088","target":"graph","created_at":"2026-05-18T00:01:38Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"graph_snapshot":{"author_claims":{"count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","strong_count":0},"builder_version":"pith-number-builder-2026-05-17-v1","claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"paper":{"abstract_excerpt":"An important task for many if not all the scientific domains is efficient knowledge integration, testing and codification. It is often solved with model construction in a controllable computational environment. In spite of that, the throughput of in-silico simulation-based observations become similarly intractable for thorough analysis. This is especially the case in molecular biology, which served as a subject for this study. In this project, we aimed to test some approaches developed to deal with the curse of dimensionality. Among these we found dimension reduction techniques especially appe","authors_text":"Emilia M. Wysocka, Laura Condon, Sahil Garg, Tirthankar Bandyopadhyay, Valery Dzutsati","cross_cats":["cs.IT","math.IT","q-bio.QM","stat.AP","stat.ML"],"headline":"","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.MN","submitted_at":"2018-04-29T23:40:44Z","title":"Building Models for Biopathway Dynamics Using Intrinsic Dimensionality Analysis"},"references":{"count":0,"internal_anchors":0,"resolved_work":0,"sample":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1804.11005","kind":"arxiv","version":3},"verdict":{"created_at":null,"id":null,"model_set":{},"one_line_summary":"","pipeline_version":null,"pith_extraction_headline":"","strongest_claim":"","weakest_assumption":""}},"verdict_id":null}}],"author_attestations":[],"timestamp_anchors":[],"storage_attestations":[],"citation_signatures":[],"replication_records":[],"corrections":[],"mirror_hints":[],"record_created":{"event_id":"sha256:5592605b38263c56e658b9a228f636dea234556665e5a07622c5e52fa726eb47","target":"record","created_at":"2026-05-18T00:01:38Z","signer":{"key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signer_id":"pith.science","signer_type":"pith_registry"},"payload":{"attestation_state":"computed","canonical_record":{"metadata":{"abstract_canon_sha256":"8951273621febbd0be17bf1efefc585ab71766f448badaa0df2ec82e2a43d6f6","cross_cats_sorted":["cs.IT","math.IT","q-bio.QM","stat.AP","stat.ML"],"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"q-bio.MN","submitted_at":"2018-04-29T23:40:44Z","title_canon_sha256":"7fdaa741360e9d80bc860b03b8392a0a3ea43940a711bc5388d7cae814a5c27a"},"schema_version":"1.0","source":{"id":"1804.11005","kind":"arxiv","version":3}},"canonical_sha256":"dd0cecc469652d647e6f258bac496155d041228dd8706aafcd76049151973da4","receipt":{"algorithm":"ed25519","builder_version":"pith-number-builder-2026-05-17-v1","canonical_sha256":"dd0cecc469652d647e6f258bac496155d041228dd8706aafcd76049151973da4","first_computed_at":"2026-05-18T00:01:38.470143Z","key_id":"pith-v1-2026-05","kind":"pith_receipt","last_reissued_at":"2026-05-18T00:01:38.470143Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","receipt_version":"0.3","signature_b64":"88chK9zLKTC6Vcyjs+eENGVTdl3D7vuYeZd1bu2gywXzHboVgWoi4gOuzbiCr0gwMMot04nAutrSN3/WucOpDw==","signature_status":"signed_v1","signed_at":"2026-05-18T00:01:38.470742Z","signed_message":"canonical_sha256_bytes"},"source_id":"1804.11005","source_kind":"arxiv","source_version":3}}},"equivocations":[],"invalid_events":[],"applied_event_ids":["sha256:5592605b38263c56e658b9a228f636dea234556665e5a07622c5e52fa726eb47","sha256:6481017c7e957edc3d0a27fc6b8cbfeafc74b1638caac45e6dcb129461eff088"],"state_sha256":"1f060c28b9069bed20ca40e286e184fd869b158f39132af625c152239b875c7c"},"bundle_signature":{"signature_status":"signed_v1","algorithm":"ed25519","key_id":"pith-v1-2026-05","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54","signature_b64":"7y6IvnsiD8qUWtk6gZsNruGLFVNiAWRME6VLF05FFmmxuNtdBuhIk34w1MUL0KcTBVZHz6faZbQIfkpRxoZTCQ==","signed_message":"bundle_sha256_bytes","signed_at":"2026-06-22T02:34:54.631793Z","bundle_sha256":"e55e0b26346e84f0113fdb59ab69ec8884ee7eb5b27d160197475ebef84194ce"}}