{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2018:4GYIJOIU5BASUZ65OMVH56CHUN","short_pith_number":"pith:4GYIJOIU","schema_version":"1.0","canonical_sha256":"e1b084b914e8412a67dd732a7ef847a34472e5f3306f3c84da30533e7057a543","source":{"kind":"arxiv","id":"1808.03746","version":1},"attestation_state":"computed","paper":{"title":"A New Boron-10 Delivery Agent for Boron Neutron Capture Therapy: Fluorescent Boron-10 Embedded Nanodiamonds","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["physics.med-ph"],"primary_cat":"physics.bio-ph","authors_text":"Bo-Rong Lin, Chien-Hsu Chen, Chien-Ping Lee, Huan Niu, Li-Chuan Liao, Srinivasu Kunuku, Tung-Yuan Hsiao, Tzung-Yuang Chen, Yu-Jen Chang","submitted_at":"2018-08-11T03:24:23Z","abstract_excerpt":"Boron neutron capture therapy is a powerful anti-cancer treatment, the success of which depends heavily on the boron delivery agent. Enabling the real-time tracing of delivery agents as they move through the body is crucial to the further development of boron neutron therapy. In this study, we fabricate highly bio-compatible boron-10 embedded nanodiamonds using physical ion implantation in conjunction with a two-step annealing process. The red fluorescence of the nanodiamonds allows their use in fluorescence microscopy and in vivo imaging systems, thereby making it possible to conduct tracking"},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1808.03746","kind":"arxiv","version":1},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"physics.bio-ph","submitted_at":"2018-08-11T03:24:23Z","cross_cats_sorted":["physics.med-ph"],"title_canon_sha256":"dd56e1738cfe60c0751c7ac7f2dfb6fedab02c6079fdddd971f199f2aa1ba63f","abstract_canon_sha256":"2d55881ae08df57fde17df8273cdbc52ad792af91cde2a7dfc9c62ffe7ea54f7"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-17T23:42:14.023133Z","signature_b64":"AxbQNV6NsK4An1a1vETwOsOBc4gkkn7HEL1gkLWeCR5X2HO0L0Uyh+2HNDi9yU3CSDbNUfDVg46LWS0lhzq9BQ==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"e1b084b914e8412a67dd732a7ef847a34472e5f3306f3c84da30533e7057a543","last_reissued_at":"2026-05-17T23:42:14.022279Z","signature_status":"signed_v1","first_computed_at":"2026-05-17T23:42:14.022279Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"A New Boron-10 Delivery Agent for Boron Neutron Capture Therapy: Fluorescent Boron-10 Embedded Nanodiamonds","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["physics.med-ph"],"primary_cat":"physics.bio-ph","authors_text":"Bo-Rong Lin, Chien-Hsu Chen, Chien-Ping Lee, Huan Niu, Li-Chuan Liao, Srinivasu Kunuku, Tung-Yuan Hsiao, Tzung-Yuang Chen, Yu-Jen Chang","submitted_at":"2018-08-11T03:24:23Z","abstract_excerpt":"Boron neutron capture therapy is a powerful anti-cancer treatment, the success of which depends heavily on the boron delivery agent. Enabling the real-time tracing of delivery agents as they move through the body is crucial to the further development of boron neutron therapy. In this study, we fabricate highly bio-compatible boron-10 embedded nanodiamonds using physical ion implantation in conjunction with a two-step annealing process. The red fluorescence of the nanodiamonds allows their use in fluorescence microscopy and in vivo imaging systems, thereby making it possible to conduct tracking"},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1808.03746","kind":"arxiv","version":1},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1808.03746","created_at":"2026-05-17T23:42:14.022532+00:00"},{"alias_kind":"arxiv_version","alias_value":"1808.03746v1","created_at":"2026-05-17T23:42:14.022532+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1808.03746","created_at":"2026-05-17T23:42:14.022532+00:00"},{"alias_kind":"pith_short_12","alias_value":"4GYIJOIU5BAS","created_at":"2026-05-18T12:32:05.422762+00:00"},{"alias_kind":"pith_short_16","alias_value":"4GYIJOIU5BASUZ65","created_at":"2026-05-18T12:32:05.422762+00:00"},{"alias_kind":"pith_short_8","alias_value":"4GYIJOIU","created_at":"2026-05-18T12:32:05.422762+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/4GYIJOIU5BASUZ65OMVH56CHUN","json":"https://pith.science/pith/4GYIJOIU5BASUZ65OMVH56CHUN.json","graph_json":"https://pith.science/api/pith-number/4GYIJOIU5BASUZ65OMVH56CHUN/graph.json","events_json":"https://pith.science/api/pith-number/4GYIJOIU5BASUZ65OMVH56CHUN/events.json","paper":"https://pith.science/paper/4GYIJOIU"},"agent_actions":{"view_html":"https://pith.science/pith/4GYIJOIU5BASUZ65OMVH56CHUN","download_json":"https://pith.science/pith/4GYIJOIU5BASUZ65OMVH56CHUN.json","view_paper":"https://pith.science/paper/4GYIJOIU","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1808.03746&json=true","fetch_graph":"https://pith.science/api/pith-number/4GYIJOIU5BASUZ65OMVH56CHUN/graph.json","fetch_events":"https://pith.science/api/pith-number/4GYIJOIU5BASUZ65OMVH56CHUN/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/4GYIJOIU5BASUZ65OMVH56CHUN/action/timestamp_anchor","attest_storage":"https://pith.science/pith/4GYIJOIU5BASUZ65OMVH56CHUN/action/storage_attestation","attest_author":"https://pith.science/pith/4GYIJOIU5BASUZ65OMVH56CHUN/action/author_attestation","sign_citation":"https://pith.science/pith/4GYIJOIU5BASUZ65OMVH56CHUN/action/citation_signature","submit_replication":"https://pith.science/pith/4GYIJOIU5BASUZ65OMVH56CHUN/action/replication_record"}},"created_at":"2026-05-17T23:42:14.022532+00:00","updated_at":"2026-05-17T23:42:14.022532+00:00"}