{"record_type":"pith_number_record","schema_url":"https://pith.science/schemas/pith-number/v1.json","pith_number":"pith:2017:4IQM2TEVFV5PO7IMF2QWVQWEHL","short_pith_number":"pith:4IQM2TEV","schema_version":"1.0","canonical_sha256":"e220cd4c952d7af77d0c2ea16ac2c43ae44b0c39d42aab54772125cd4c3c60b2","source":{"kind":"arxiv","id":"1706.01291","version":6},"attestation_state":"computed","paper":{"title":"On the sample mean after a group sequential trial","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["stat.TH"],"primary_cat":"math.ST","authors_text":"Anna Ivanova, Ben Berckmoes, Geert Molenberghs","submitted_at":"2017-06-05T12:35:25Z","abstract_excerpt":"A popular setting in medical statistics is a group sequential trial with independent and identically distributed normal outcomes, in which interim analyses of the sum of the outcomes are performed. Based on a prescribed stopping rule, one decides after each interim analysis whether the trial is stopped or continued. Consequently, the actual length of the study is a random variable. It is reported in the literature that the interim analyses may cause bias if one uses the ordinary sample mean to estimate the location parameter. For a generic stopping rule, which contains many classical stopping "},"verification_status":{"content_addressed":true,"pith_receipt":true,"author_attested":false,"weak_author_claims":0,"strong_author_claims":0,"externally_anchored":false,"storage_verified":false,"citation_signatures":0,"replication_records":0,"graph_snapshot":true,"references_resolved":false,"formal_links_present":false},"canonical_record":{"source":{"id":"1706.01291","kind":"arxiv","version":6},"metadata":{"license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","primary_cat":"math.ST","submitted_at":"2017-06-05T12:35:25Z","cross_cats_sorted":["stat.TH"],"title_canon_sha256":"8f12a799de0b29b8b04c10a0f659e59b4162a14a3f0780893ce6773440daf9a8","abstract_canon_sha256":"3b904ed980a3f77396aac2d535bc1ca32ce858883bea094bbad0500727a08243"},"schema_version":"1.0"},"receipt":{"kind":"pith_receipt","key_id":"pith-v1-2026-05","algorithm":"ed25519","signed_at":"2026-05-18T00:19:42.245075Z","signature_b64":"/85jVCtgPwz1q/OpO9kQIynrWbKf+TZbyGRmuv1KHqHIDs0AGkXv9xy/lqBEnjHrjBNhki857Ay0KIvGig7/DA==","signed_message":"canonical_sha256_bytes","builder_version":"pith-number-builder-2026-05-17-v1","receipt_version":"0.3","canonical_sha256":"e220cd4c952d7af77d0c2ea16ac2c43ae44b0c39d42aab54772125cd4c3c60b2","last_reissued_at":"2026-05-18T00:19:42.244308Z","signature_status":"signed_v1","first_computed_at":"2026-05-18T00:19:42.244308Z","public_key_fingerprint":"8d4b5ee74e4693bcd1df2446408b0d54"},"graph_snapshot":{"paper":{"title":"On the sample mean after a group sequential trial","license":"http://arxiv.org/licenses/nonexclusive-distrib/1.0/","headline":"","cross_cats":["stat.TH"],"primary_cat":"math.ST","authors_text":"Anna Ivanova, Ben Berckmoes, Geert Molenberghs","submitted_at":"2017-06-05T12:35:25Z","abstract_excerpt":"A popular setting in medical statistics is a group sequential trial with independent and identically distributed normal outcomes, in which interim analyses of the sum of the outcomes are performed. Based on a prescribed stopping rule, one decides after each interim analysis whether the trial is stopped or continued. Consequently, the actual length of the study is a random variable. It is reported in the literature that the interim analyses may cause bias if one uses the ordinary sample mean to estimate the location parameter. For a generic stopping rule, which contains many classical stopping "},"claims":{"count":0,"items":[],"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"source":{"id":"1706.01291","kind":"arxiv","version":6},"verdict":{"id":null,"model_set":{},"created_at":null,"strongest_claim":"","one_line_summary":"","pipeline_version":null,"weakest_assumption":"","pith_extraction_headline":""},"references":{"count":0,"sample":[],"resolved_work":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57","internal_anchors":0},"formal_canon":{"evidence_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"author_claims":{"count":0,"strong_count":0,"snapshot_sha256":"258153158e38e3291e3d48162225fcdb2d5a3ed65a07baac614ab91432fd4f57"},"builder_version":"pith-number-builder-2026-05-17-v1"},"aliases":[{"alias_kind":"arxiv","alias_value":"1706.01291","created_at":"2026-05-18T00:19:42.244451+00:00"},{"alias_kind":"arxiv_version","alias_value":"1706.01291v6","created_at":"2026-05-18T00:19:42.244451+00:00"},{"alias_kind":"doi","alias_value":"10.48550/arxiv.1706.01291","created_at":"2026-05-18T00:19:42.244451+00:00"},{"alias_kind":"pith_short_12","alias_value":"4IQM2TEVFV5P","created_at":"2026-05-18T12:31:00.734936+00:00"},{"alias_kind":"pith_short_16","alias_value":"4IQM2TEVFV5PO7IM","created_at":"2026-05-18T12:31:00.734936+00:00"},{"alias_kind":"pith_short_8","alias_value":"4IQM2TEV","created_at":"2026-05-18T12:31:00.734936+00:00"}],"events":[],"event_summary":{},"paper_claims":[],"inbound_citations":{"count":0,"internal_anchor_count":0,"sample":[]},"formal_canon":{"evidence_count":0,"sample":[],"anchors":[]},"links":{"html":"https://pith.science/pith/4IQM2TEVFV5PO7IMF2QWVQWEHL","json":"https://pith.science/pith/4IQM2TEVFV5PO7IMF2QWVQWEHL.json","graph_json":"https://pith.science/api/pith-number/4IQM2TEVFV5PO7IMF2QWVQWEHL/graph.json","events_json":"https://pith.science/api/pith-number/4IQM2TEVFV5PO7IMF2QWVQWEHL/events.json","paper":"https://pith.science/paper/4IQM2TEV"},"agent_actions":{"view_html":"https://pith.science/pith/4IQM2TEVFV5PO7IMF2QWVQWEHL","download_json":"https://pith.science/pith/4IQM2TEVFV5PO7IMF2QWVQWEHL.json","view_paper":"https://pith.science/paper/4IQM2TEV","resolve_alias":"https://pith.science/api/pith-number/resolve?arxiv=1706.01291&json=true","fetch_graph":"https://pith.science/api/pith-number/4IQM2TEVFV5PO7IMF2QWVQWEHL/graph.json","fetch_events":"https://pith.science/api/pith-number/4IQM2TEVFV5PO7IMF2QWVQWEHL/events.json","actions":{"anchor_timestamp":"https://pith.science/pith/4IQM2TEVFV5PO7IMF2QWVQWEHL/action/timestamp_anchor","attest_storage":"https://pith.science/pith/4IQM2TEVFV5PO7IMF2QWVQWEHL/action/storage_attestation","attest_author":"https://pith.science/pith/4IQM2TEVFV5PO7IMF2QWVQWEHL/action/author_attestation","sign_citation":"https://pith.science/pith/4IQM2TEVFV5PO7IMF2QWVQWEHL/action/citation_signature","submit_replication":"https://pith.science/pith/4IQM2TEVFV5PO7IMF2QWVQWEHL/action/replication_record"}},"created_at":"2026-05-18T00:19:42.244451+00:00","updated_at":"2026-05-18T00:19:42.244451+00:00"}